Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Neuroplasticity01:01

Neuroplasticity

648
Neuroplasticity reflects the brain's remarkable capacity to adapt and evolve, responding dynamically to learning, experiences, or injury by reorganizing its neural circuitry. This reorganization involves creating new neural connections and refining old ones through a series of biological processes that contribute to the brain's lifelong development and adaptability.
648
Long-term Potentiation01:35

Long-term Potentiation

55.5K
Long-term potentiation, or LTP, is one of the ways by which synaptic plasticity—changes in the strength of chemical synapses—can occur in the brain. LTP is the process of synaptic strengthening that occurs over time between pre- and postsynaptic neuronal connections. The synaptic strengthening of LTP works in opposition to the synaptic weakening of long-term depression (LTD) and together are the main mechanisms that underlie learning and memory.
55.5K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Prediction of cognitive performance by demographics, sleep, and brain morphometry: machine learning findings from ENIGMA-Sleep Working Group.

Research square·2026
Same author

Chronotype and Time of Day Effects in Oddball Task Performance: Behavioural and Cerebral Correlates.

Journal of sleep research·2026
Same author

Breaking the nap habit: one-year nap restriction mitigates memory decline in older adults.

GeroScience·2026
Same author

Author Correction: Pr and Pfr structures of plant phytochrome A.

Nature communications·2026
Same author

PEO-sheathed liquid jets increase sample delivery stability for serial femtosecond X-ray crystallography.

Scientific reports·2026
Same author

Habitual napping in older adults is accompanied by altered heat-loss rhythms across the circadian cycle and reduced coupling between pre-sleep thermoregulatory dynamics and sleep initiation.

Temperature (Austin, Tex.)·2026
Same journal

miR-19a-3p and miR-19b-3p Promote Microglia Activation Associated With Neuroinflammation.

Journal of neuroscience research·2026
Same journal

Correction to "Chronic Nicotine and Smoke Treatment Modulate Dopaminergic Activities in Ventral Tegmental Area and Nucleus Accumbens and the γ-Aminobutyric Acid Type B Receptor Expression of the Rat Prefrontal Cortex".

Journal of neuroscience research·2026
Same journal

EXPRESSION OF CONCERN: Hypoxia-Induced Deactivation of NGF-Mediated ERK1/2 Signaling in Hippocampal Cells: Neuroprotection by Acetyl-L-Carnitine.

Journal of neuroscience research·2026
Same journal

DKK1 Targeting in Corneal Schwann Cells Rescues Axonal Regeneration and Mechanosensory Function After Corneal Injury.

Journal of neuroscience research·2026
Same journal

An Examination of Task-Evoked fMRI Data Processing in Functional Connectivity.

Journal of neuroscience research·2026
Same journal

Association of Interhemispheric Structural Integrity With Transcallosal Interhemispheric Inhibition in People With Chronic Stroke.

Journal of neuroscience research·2026
See all related articles

Related Experiment Video

Updated: Aug 10, 2025

Author Spotlight: Investigating the Effects of Mind-Body-Movement Practices on Brain Function
06:17

Author Spotlight: Investigating the Effects of Mind-Body-Movement Practices on Brain Function

Published on: January 26, 2024

2.1K

Sleep-dependent structural neuroplasticity after a spatial navigation task: A diffusion imaging study.

Thomas Villemonteix1,2, Michele Guerreri3, Michele Deantoni1,4

  • 1UR2NF-Neuropsychology and Functional Neuroimaging Research Unit affiliated at CRCN - Centre for Research in Cognition and Neurosciences and UNI - ULB Neuroscience Institute, Université Libre de Bruxelles (ULB), Brussels, Belgium.

Journal of Neuroscience Research
|February 14, 2023
PubMed
Summary
This summary is machine-generated.

Post-learning sleep rapidly remodels brain structures, enhancing navigation skills. This study reveals sleep

Keywords:
NODDIdiffusion imagingsleepspatial navigationstructural

More Related Videos

Modeling the Functional Network for Spatial Navigation in the Human Brain
05:55

Modeling the Functional Network for Spatial Navigation in the Human Brain

Published on: October 13, 2023

1.1K
Using MazeSuite and Functional Near Infrared Spectroscopy to Study Learning in Spatial Navigation
20:12

Using MazeSuite and Functional Near Infrared Spectroscopy to Study Learning in Spatial Navigation

Published on: October 8, 2011

30.6K

Related Experiment Videos

Last Updated: Aug 10, 2025

Author Spotlight: Investigating the Effects of Mind-Body-Movement Practices on Brain Function
06:17

Author Spotlight: Investigating the Effects of Mind-Body-Movement Practices on Brain Function

Published on: January 26, 2024

2.1K
Modeling the Functional Network for Spatial Navigation in the Human Brain
05:55

Modeling the Functional Network for Spatial Navigation in the Human Brain

Published on: October 13, 2023

1.1K
Using MazeSuite and Functional Near Infrared Spectroscopy to Study Learning in Spatial Navigation
20:12

Using MazeSuite and Functional Near Infrared Spectroscopy to Study Learning in Spatial Navigation

Published on: October 8, 2011

30.6K

Area of Science:

  • Neuroscience
  • Neuroimaging
  • Sleep Research

Background:

  • Microstructural neuroplasticity's link to sleep is not well understood.
  • Learning involves reorganizing functional brain networks, but sleep's role in structural changes is unclear.
  • Existing methods struggle to differentiate changes in neurites from other cellular components.

Purpose of the Study:

  • To investigate how post-training sleep affects structural neuroplasticity markers.
  • To utilize advanced diffusion tensor imaging (DTI) and neurite orientation dispersion and density imaging (NODDI) to measure these changes.
  • To explore sleep's impact on specific brain regions involved in learning and memory.

Main Methods:

  • Thirty-four healthy adults underwent diffusion-weighted imaging (DWI) before and after navigation learning.
  • Participants were either sleep-deprived (SD) or randomly slept (RS) overnight.
  • Scans were repeated after a 2-night recovery sleep period, assessing learning in an extended environment.

Main Results:

  • Navigation learning reduced diffusion tensor imaging (DTI) and neurite orientation dispersion and density imaging (NODDI) parameters in cortical and subcortical regions.
  • Post-learning sleep was associated with significant changes in neurite density index (NDI) and free water fraction (FWF) in basal ganglia and hippocampal structures.
  • These changes suggest rapid, sleep-dependent remodeling of neurites and glial cells.

Conclusions:

  • Sleep plays a crucial role in the rapid microstructural remodeling of brain regions supporting learning and memory.
  • Advanced imaging techniques like NODDI can distinguish between neurite and glial cell contributions to neuroplasticity.
  • Findings highlight the importance of sleep for consolidating newly acquired navigation skills.