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A Descriptive Review of Cannabis sativa Patents for Cancer Treatment
Isabela Fernandes Pereira1, Ana Maria Santos Oliveira2, Anamaria Mendonça Santos3
1Faculty of Pharmacy, Federal University of Bahia, Campus Ondina, Salvador, BA, Brazil.
Background:
Cannabis use for tumor treatment has been explored in several areas, and its potential for tumor remission is currently being studied after the discovery of the endogenous cannabinoid.
Objective:
The study aimed to conduct a critical patent review to identify and explore the latest advances and therapeutic strategies using Cannabis to treat cancer.
Methods:
The research was carried out in the free and online database Espacenet, using the descriptors "cancer" and "Cannabis or cannabidiol" in the title or abstract. A total of 95 patents were identified for preliminary evaluation in the database. Six duplicate patents were excluded, 12 referring to traditional Chinese medicine and 36 with a title in disagreement with the scope of this review. In addition the final selection involved 21 patents that were in line with the objective of the study.
Results:
As observed in the reading of patents, the interest of pharmaceutical industries and researchers and the development of new products to fight cancer have increased in recent years. The main cannabinoids present in the patents are tetrahydrocannabinol, cannabidiol, and hemp. Moreover, the patents were classified and the main applicant countries were the United States followed by Japan, with a higher filing rate in 2019 and, mainly by the industry.
Conclusion:
In conclusion we can say that, the importance of parliamentary approval in the cultivation and investments that, in addition to bringing innovation to the industrial sector, enriches research in the area, contributing to the creation of new medicines.
Insights
This patent review reveals a growing interest in cannabis-based cancer treatments. Research highlights tetrahydrocannabinol and cannabidiol as key compounds driving innovation in new cancer medicines.
Area of Science:
- Oncology
- Pharmacology
- Intellectual Property Law
Background:
- Cannabis compounds are being investigated for their potential in cancer treatment and tumor remission.
- The discovery of endogenous cannabinoids has spurred research into cannabis-based therapies.
Approach:
- A critical patent review was conducted using the Espacenet database.
- Search terms included "cancer" and "Cannabis or cannabidiol" in titles or abstracts.
- 21 relevant patents were selected after excluding duplicates and irrelevant studies.
Key Points:
- Pharmaceutical industries and researchers show increasing interest in cannabis for cancer.
- Tetrahydrocannabinol (THC), cannabidiol (CBD), and hemp are the primary cannabinoids in reviewed patents.
- The United States and Japan lead in patent filings, with a surge in 2019, primarily from industry.
Conclusions:
- Parliamentary approval for cannabis cultivation and investment is crucial for innovation.
- Increased investment fosters advancements in cannabis research for novel cancer medicines.
- This research contributes to the development of new therapeutic strategies in oncology.
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