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Updated: Aug 10, 2025
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Systematic Assessment of Mammalian Skull Specimens for Dental and Temporomandibular Joint Pathology
Published on: August 22, 2022
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Synchronous jawbone diseases: a multicenter retrospective study.
Diogo Dos Santos da Mata Rezende1, Lucas Lacerda de Souza1, Daniel Cavalléro Colares Uchôa1
1Universidade Estadual de Campinas - Unicamp, Piracicaba Dental School, Department of Oral Diagnosis, Piracicaba, SP, Brazil.
Brazilian Oral Research
|February 15, 2023
Summary
This case series highlights synchronous jawbone diseases, finding florid osseous dysplasia and Gorlin-Goltz syndrome most common. Early diagnosis often relies on clinical and radiologic data, sometimes needing further lab tests.
Area of Science:
- Oral Radiology and Pathology
- Dental Medicine
- Pathology
Background:
- Synchronous jawbone diseases are rare conditions affecting bone development.
- Accurate diagnosis is crucial for appropriate patient management.
- Previous case series on synchronous jawbone diseases are limited.
Purpose of the Study:
- To present an original case series of synchronous jawbone diseases.
- To analyze the clinical, radiographic, and laboratory characteristics of these lesions.
- To identify the most frequent types and locations of synchronous jawbone diseases.
Main Methods:
- Retrospective analysis of patient data over 13 years from three diagnostic centers in Brazil.
- Inclusion of 72 cases of synchronous jawbone diseases.
- Tabulation and analysis of clinical, radiographic, and laboratory findings.
Main Results:
- Florid osseous dysplasia, Gorlin-Goltz syndrome, and cherubism were the most frequent diagnoses.
- The posterior mandible was the most common site of manifestation.
- Florid osseous dysplasia and Gorlin-Goltz syndrome accounted for two-thirds of the cases.
Conclusions:
- Most synchronous jawbone lesions can be diagnosed using demographic, clinical, and radiologic information.
- Histopathologic and biochemical analyses (calcium, phosphorus, alkaline phosphatase) may be necessary for definitive diagnosis.
- This case series contributes valuable data on the presentation of synchronous jawbone diseases in a Brazilian population.
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