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Sensor Network for Continuous Tablet Manufacturing
Sudarshan Ganesh1, Mariana Moreno1, Jianfeng Liu1
1School of Chemical Engineering, Purdue University, West Lafayette, IN 47907, USA.
Abstract:
The progress in the mechanistic understanding of the unit operations and the availability of multiple sensor technologies enable the inline implementation of data reconciliation and gross error detection methods in continuous pharmaceutical manufacturing. In this work, we demonstrate the benefits of accurate real-time monitoring of the process state in a continuous tableting process, with case studies representative of common situations in pilot-plant or manufacturing line implementation.

