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Brain Imaging

Brain Imaging

Brain imaging technologies provide critical insights into both the structure and function of the human brain, enabling medical professionals and researchers to diagnose, study, and treat neurological disorders or psychiatric disorders more effectively.
These technologies include computerized axial tomography (CAT or CT scans), positron-emission tomography (PET scans), magnetic resonance imaging (MRI), functional magnetic resonance imaging (fMRI), and Transcranial Magnetic...

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A Pipeline for 3D Multimodality Image Integration and Computer-assisted Planning in Epilepsy Surgery

A Pipeline for 3D Multimodality Image Integration and Computer-assisted Planning in Epilepsy Surgery

Published on: May 20, 2016

Neurological update: structural and functional imaging in epilepsy surgery.

Katie Yoganathan^1,2, Naveed Malek³, Emma Torzillo⁴

¹University of Oxford and Oxford University Hospitals, Oxford, UK. katie.yoganathan@ndcn.ox.ac.uk.

Journal of Neurology

|February 15, 2023

Summary

Advanced brain imaging techniques like MRI and PET scans are crucial for planning epilepsy surgery and predicting outcomes in patients with drug-resistant focal epilepsy. These methods help pinpoint seizure origins, guiding treatment and improving patient care.

Keywords:

EEG Epilepsy FMRI PET SPECT Surgery

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Published on: April 15, 2015

Area of Science:

Neurology
Radiology
Neurosurgery

Background:

Drug-resistant focal epilepsy requires precise localization of the epileptogenic zone for effective surgical planning.
Electroencephalography (EEG) is essential, but advanced imaging complements it in identifying seizure origins.

Approach:

This review examines the role of various structural and functional neuroimaging modalities, including CT, MRI, fMRI, SPECT, and PET.
It highlights how these techniques aid in preoperative work-up for medically refractory epilepsy.

Key Points:

In MRI-negative cases, PET (hypometabolism) and SPECT (hyperperfusion) can localize the seizure focus.
Multimodal imaging helps characterize focal pathology, its relation to eloquent brain areas, and network connectivity.
Imaging guides the placement of intracranial EEG electrodes when necessary.

Conclusions:

Advanced neuroimaging is vital for optimizing surgical planning and predicting outcomes in drug-resistant focal epilepsy.
These less invasive techniques improve the identification and characterization of the epileptogenic zone.
This review provides a practical guide for selecting investigations and interpreting findings for patient management.