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Targeted Cancer Therapies02:57

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The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
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Related Experiment Video

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Y-90 Radioembolization and PD-1 Inhibitor as Neoadjuvant Treatment in Hepatocellular Carcinoma
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Interventional nanotheranostics in hepatocellular carcinoma.

Vivek P Chavda1, Pankti C Balar2, Srushti B Patel3

  • 1Department of Pharmaceutics and Pharmaceutical Technology, L.M. College of Pharmacy, Ahmedabad, India.

Nanotheranostics
|February 16, 2023
PubMed
Summary

Interventional nanotheranostics combines diagnosis and therapy for efficient disease management. This advanced drug delivery system, using nanoparticles, shows promise for treating diseases like Hepatocellular Carcinoma with minimal side effects.

Keywords:
HCCInterventional NanotheranosticsLiver CancerNanoparticleSELEX

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Area of Science:

  • Biomedical Engineering
  • Nanotechnology
  • Oncology

Background:

  • Interventional nanotheranostics integrates diagnostic and therapeutic capabilities for enhanced disease management.
  • Current limitations in disease detection and treatment necessitate innovative approaches.
  • Nanoparticles offer potential for targeted drug delivery and improved therapeutic outcomes.

Purpose of the Study:

  • To review the role and potential of interventional nanotheranostics in disease treatment.
  • To highlight the application of nanotheranostics in managing Hepatocellular Carcinoma.
  • To discuss the mechanisms, advantages, and challenges of nanotheranostic systems.

Main Methods:

  • Review of current literature on interventional nanotheranostics.
  • Analysis of nanoparticle-based drug delivery systems (e.g., Gold NPs, Carbon NPs, Silicon NPs).
  • Examination of diagnostic imaging integration with therapeutic delivery.

Main Results:

  • Nanotheranostics enables early disease detection, targeted drug delivery, and reduced damage to healthy tissues.
  • The system demonstrates high efficiency in disease management, particularly for Hepatocellular Carcinoma.
  • Identified pitfalls in current systems and proposed nanotheranostics as a superior alternative.

Conclusions:

  • Interventional nanotheranostics represents a significant advancement in precision medicine.
  • Despite current challenges, nanotheranostics holds substantial promise for future therapeutic applications.
  • Further research and development are crucial to overcome existing hindrances and realize the full potential of this technology.