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Ocular presentation of Mpox in a healthy child without known exposure
Lauren C Ditta1, Peter Wojcik2, Timothy D Minniear3
1Department of Ophthalmology, University of Tennessee Health Science Center, Memphis, Tennessee; Le Bonheur Neuroscience Institute, Le Bonheur Children's Hospital, Memphis, Tennessee; St. Jude Children's Research Hospital, Memphis, Tennessee.
Abstract:
Ocular complications can occur from Mpox infection and are increasingly being reported, with the rise in worldwide cases. There are few reports of Mpox outside of endemic areas in healthy children. We describe a healthy girl with Mpox who presented with ocular symptoms after experiencing trauma to the eye; this case highlights a pediatric case of Mpox localized to the eye and periorbital region. In the absence of a prodromal phase, the ocular signs and symptoms were initially thought to represent more common, benign etiologies. This case underscores the importance of considering Mpox, even in the absence of known exposures or in the setting of an atypical presentation.
Insights
Mpox can cause eye complications, even in healthy children. This case highlights a pediatric Mpox infection localized to the eye, emphasizing the need for consideration in atypical presentations.
Area of Science:
- Ophthalmology
- Infectious Diseases
- Pediatrics
Background:
- Mpox (formerly monkeypox) is a viral disease with increasing global incidence.
- Ocular complications are recognized but rarely reported in healthy children outside endemic regions.
- Atypical presentations can delay diagnosis.
Observation:
- A healthy pediatric patient presented with ocular symptoms following eye trauma.
- Initial symptoms mimicked common, benign eye conditions due to the absence of a prodromal phase.
- The Mpox infection was localized to the eye and periorbital area.
Findings:
- This case details a rare pediatric presentation of Mpox.
- Ocular Mpox occurred in a healthy child without a typical prodrome or known exposure.
- The localized ocular and periorbital symptoms were initially misattributed.
Implications:
- Highlights the importance of considering Mpox in pediatric ocular emergencies, even with atypical signs.
- Underscores the need for heightened awareness of Mpox in non-endemic areas.
- Emphasizes the diagnostic challenge posed by Mpox presenting solely with ocular manifestations.
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