Ocular presentation of Mpox in a healthy child without known exposure

Lauren C Ditta1, Peter Wojcik2, Timothy D Minniear3

  • 1Department of Ophthalmology, University of Tennessee Health Science Center, Memphis, Tennessee; Le Bonheur Neuroscience Institute, Le Bonheur Children's Hospital, Memphis, Tennessee; St. Jude Children's Research Hospital, Memphis, Tennessee.

Insights

Mpox can cause eye complications, even in healthy children. This case highlights a pediatric Mpox infection localized to the eye, emphasizing the need for consideration in atypical presentations.

Area of Science:

  • Ophthalmology
  • Infectious Diseases
  • Pediatrics

Background:

  • Mpox (formerly monkeypox) is a viral disease with increasing global incidence.
  • Ocular complications are recognized but rarely reported in healthy children outside endemic regions.
  • Atypical presentations can delay diagnosis.

Observation:

  • A healthy pediatric patient presented with ocular symptoms following eye trauma.
  • Initial symptoms mimicked common, benign eye conditions due to the absence of a prodromal phase.
  • The Mpox infection was localized to the eye and periorbital area.

Findings:

  • This case details a rare pediatric presentation of Mpox.
  • Ocular Mpox occurred in a healthy child without a typical prodrome or known exposure.
  • The localized ocular and periorbital symptoms were initially misattributed.

Implications:

  • Highlights the importance of considering Mpox in pediatric ocular emergencies, even with atypical signs.
  • Underscores the need for heightened awareness of Mpox in non-endemic areas.
  • Emphasizes the diagnostic challenge posed by Mpox presenting solely with ocular manifestations.