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Updated: Aug 9, 2025

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Development of New Therapeutic Applications Using Microfluidics
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Global or local: The future of biotech
Vincent Tse1, Liang Schweizer1
1HiFiBiO Therapeutics, 237 Putnam Avenue, Cambridge, MA 02139, USA.
Drug Discovery Today
|February 16, 2023
Summary
Born-global biotechnology (biotech) startups, by accessing global resources and talent early, are better positioned for success. This approach addresses innovation, resource, and talent challenges for faster growth.
Area of Science:
- Biotechnology
- Pharmaceutical Sciences
- Entrepreneurship
Background:
- Biotech startups traditionally focus domestically, limiting access to resources and talent.
- Developing novel therapeutics demands substantial investment and long-term commitment.
- Current industry challenges necessitate innovative strategies for growth and success.
Purpose of the Study:
- To advocate for the 'born-global' approach in biotechnology startups.
- To demonstrate how born-global biotechs can overcome industry challenges.
- To provide a framework for achieving success as a born-global biotech.
Main Methods:
- Comparative analysis of domestic vs. born-global biotech models.
- Literature review on innovation, resource management, and talent acquisition in biotech.
- Development of an operational framework based on the FlyWheel concept.
Main Results:
- Born-global biotechs exhibit enhanced capacity to address innovation and resource constraints.
- Global access mitigates limitations in talent diversity.
- Capital efficiency is crucial for maximizing born-global advantages.
Conclusions:
- Adopting a born-global strategy is advantageous for biotech startup success.
- The FlyWheel concept offers a practical operational model for born-global biotechs.
- Early global integration is key to navigating complex therapeutic development landscapes.
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