Thromboembolic Disorder in COVID-19 Infection

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Shawn Lee1, Joseph Gunderson2, Raza Mushtaq3

  • 1Department of Cardiovascular Diseases, Mount Sinai St. Luke's Icahn School of Medicine, 1111 Amsterdam Ave, New York, NY 10025, USA.

Current Medical Imaging
|February 16, 2023
PubMed

Insights

Severe COVID-19 infections can cause coagulopathy, leading to multi-systemic thromboembolic events and increased mortality. This review details COVID-19

Area of Science:

  • Medical Science
  • Infectious Diseases
  • Pathophysiology

Background:

  • Coronavirus disease (COVID-19) is a global pandemic impacting millions worldwide.
  • Severe COVID-19 is associated with coagulopathy, a condition affecting blood clotting.
  • This coagulopathy contributes to multi-systemic thromboembolic manifestations and increased mortality.

Approach:

  • This review synthesizes current data on COVID-19-related thromboembolic complications.
  • Emphasis is placed on understanding the underlying pathophysiology.
  • Clinical management strategies and radiological findings are also highlighted.

Key Points:

  • COVID-19 coagulopathy presents as a significant risk factor for thromboembolic events.
  • These events can affect multiple organ systems, complicating patient outcomes.
  • A strong correlation exists between coagulopathy and mortality in severe COVID-19 cases.

Conclusions:

  • Understanding the pathophysiology of COVID-19 coagulopathy is crucial for effective management.
  • Early recognition and management of thromboembolic complications can improve patient prognosis.
  • Radiological assessment plays a vital role in diagnosing and monitoring these manifestations.

Keywords:
COVID-19ChinaCoronaviruscoagulation parameterscoagulopathythromboembolic disorders

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