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Subdural CMOS optical probe (SCOPe) for bidirectional neural interfacing
Biorxiv : the Preprint Server for Biology
|February 17, 2023
Summary
Researchers developed an ultrathin, implantable optical probe for brain-machine interfaces. This new device enables precise monitoring and manipulation of neural activity, paving the way for future human applications.
Area of Science:
- Neuroscience
- Biomedical Engineering
- Optoelectronics
Background:
- Optical neurotechnologies offer high-precision neural monitoring and manipulation.
- Current devices are too bulky for full implantation, hindering human translation.
- A minimally invasive, implantable form factor is crucial for advancing brain-machine interfaces.
Approach:
- Developed the subdural CMOS Optical Probe (SCOPe), an ultrathin, miniaturized device.
- Leveraged advances in microelectronics and heterogeneous optoelectronic packaging.
- Designed SCOPe for bidirectional optical stimulation and recording within the subdural space.
Key Points:
- SCOPe is thin enough for subdural placement in the primate brain.
- The device integrates microelectronics and optoelectronics for advanced functionality.
- Enables precise, large-area monitoring and manipulation of neural activity.
Conclusions:
- SCOPe represents a significant advancement towards fully implantable optical neurotechnology.
- This technology defines a path for the human translation of next-generation brain-machine interfaces.
- The development addresses the critical need for noninvasive, miniaturized neural interfaces.
