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Updated: Aug 9, 2025

Natural Product Discovery with LC-MS/MS Diagnostic Fragmentation Filtering: Application for Microcystin Analysis
Published on: May 31, 2019
Research advance in the distribution and ecotoxicological effects of microcystins in aquatic ecosystem
Yu Qiu1,2,3, Zeng-Ling Ma1,2,3, Zi-Yi Zhang3
1National and Local Joint Engineering Research Center of Ecological Treatment Technology for Urban Water Pollution, Wenzhou University, Wenzhou 325035, Zhejiang, China.
Abstract:
Cyanotoxins produced by the toxic cyanobacteria is a great threat to global freshwater ecosystems, with hepatotoxic microcystins (MCs) as the most widely distributed and harmful ones. MCs have negative impacts on the structure, function and stability of aquatic ecosystems, posing threats to human health. In this study, we reviewed the distribution of MCs in waterbody, sediments, and different groups of aquatic animals. The toxicity mechanisms of MCs were also reviewed. The ecotoxicological effects of MCs on aquatic animals, aquatic and terrestrial plants, human health risk were summarized. Several biological methods about the prevention and control of MCs were mentioned. Many aspects about MCs that need to be further studied were proposed, aiming to provide a scientific basis for risk assessment and management of MCs.

