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Use of Pediatric Outcomes Data Collection Instrument to Evaluate Functional Outcomes in Multiple Hereditary Exostoses
Nathalia Sundin Palmeira de Oliveira1, Marcela Rocha Dias da Silva2, Camila Bedeschi Rego de Mattos3
1Oncology Orthopedist, Orthopaedic department, Hospital Universitário Pedro Ernesto (HUPE-UERJ), Rio de Janeiro, RJ.
Insights
The Pediatric Outcomes Data Collection Instrument (PODCI) effectively measures quality of life in children with multiple hereditary exostosis (MHE), showing lower functional levels compared to healthy peers.
Area of Science:
- Orthopedics
- Pediatric Health
- Quality of Life Research
Background:
- The Pediatric Outcomes Data Collection Instrument (PODCI) is a validated tool for assessing quality of life in pediatric musculoskeletal conditions.
- Multiple hereditary exostosis (MHE) is a genetic disorder affecting bone development, with limited research on its impact on children's general health status and daily functioning.
- Existing studies on MHE primarily focus on surgical interventions and deformity correction, neglecting the broader health and functional implications for pediatric patients.
Purpose of the Study:
- To evaluate the functional levels and quality of life in pediatric patients diagnosed with multiple hereditary exostosis (MHE) using the PODCI questionnaire.
- To establish a baseline understanding of how MHE affects pain, function, and daily activities in children.
- To explore the utility of the PODCI in assessing outcomes for MHE patients.
Main Methods:
- A cross-sectional study involving 34 pediatric patients with MHE and their families.
- Prospective administration of the PODCI questionnaire to assess functional status.
- Statistical analysis including Student and Welch t tests for group comparisons, Wilcoxon signed rank test for parent-child report differences, and Spearman test for correlation with physical examination findings.
Main Results:
- Pediatric patients with MHE demonstrated significantly lower PODCI scores across all domains compared to unaffected children (P < 0.05).
- Statistically significant differences were observed between parent and child reports in the pain and comfort domain (P < 0.5).
- A significant negative correlation was found between physical examination findings and PODCI scores, indicating poorer function with more severe physical signs.
Conclusions:
- The PODCI questionnaire is a capable tool for evaluating functional outcomes in pediatric patients with multiple hereditary exostosis (MHE).
- The findings highlight the significant impact of MHE on the quality of life and functional status of affected children.
- Further research utilizing the PODCI can aid in developing targeted interventions and improving care for children with MHE.
Background:
The Pediatric Outcomes Data Collection Instrument (PODCI) is a validated quality-of-life questionnaire with 6 domains designed to provide a standardized method of measuring outcomes in pediatric musculoskeletal conditions. To our knowledge there are no reports on its use in children with multiple hereditary exostosis (MHE).
Questions/Purposes:
Most published studies on MHE patients have described the efficacy of specific surgical techniques or the specification of deformities. Little is known about the general health status of pediatric patients, the severity of pain, loss of function, and how MHE influences the activities of daily life. We aim to assess the functional levels of MHE pediatric patients with PODCI questionnaire.
Patients And Methods:
As a cross-sectional study, we prospectively administered PODCI to 34 pediatric patients diagnosed with MHE and their families. The score distributions were compared with values published earlier for children and adolescents without musculoskeletal disorders using the Student and Welch t tests. Parents and adolescents' reports were compared using Wilcoxon signed rank test. Physical examination and PODCI score relation were evaluated by Spearman test.
Results:
Children with MHE have significantly lower scores ( P <0,05) in comparison with unaffected children in all domains using the Student and Welch t test. Parents score differs from children score with statistically relevance in pain and comfort domain ( P <0,5). The Spearman test showed a negative correlation between physical examination and PODCI score with statistical significance.
Conclusions:
These results point towards PODCI's capacity in evaluating functional outcomes of pediatric patients with MHE.
Level Of Evidence:
Diagnostic Study, Level III.
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