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Acute Pyelonephritis II: Diagnostic Studies and Management01:28

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Introduction:For diagnosing acute pyelonephritis, a comprehensive patient history is collected to identify symptoms such as dysuria, frequent or urgent urination, flank pain, or costovertebral angle (CVA) tenderness that may suggest a kidney infection.Physical ExaminationDuring the physical examination, CVA tenderness is assessed. This involves gentle percussion over the costovertebral angle, where tenderness often indicates a kidney infection.Diagnostic TestsUrinalysis: Used to identify white...
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Related Experiment Video

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International Expert Consensus and Recommendations for Neonatal Pneumothorax Ultrasound Diagnosis and Ultrasound-guided Thoracentesis Procedure
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UK consensus definitions for necrotising otitis externa: a Delphi study.

Susanne H Hodgson1,2, Maha M Khan3, Maia Patrick-Smith4

  • 1Department of Microbiology, Oxford University Hospitals NHS Foundation Trust, Oxford, Oxfordshire, UK.

BMJ Open
|February 22, 2023
PubMed
Summary
This summary is machine-generated.

This study established consensus definitions for necrotising otitis externa (NOE) to improve diagnosis and research. These definitions were developed through expert consensus, aiding clinical practice for this neglected condition.

Keywords:
Adult otolaryngologyINFECTIOUS DISEASESMICROBIOLOGYOTOLARYNGOLOGYRADIOLOGY & IMAGING

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Area of Science:

  • Otolaryngology
  • Infectious Diseases
  • Medical Diagnostics

Background:

  • Necrotising otitis externa (NOE) lacks standardized diagnostic criteria, hindering clinical management and research.
  • Previous studies on NOE have been limited by inconsistent definitions, impacting comparability and progress.
  • A need exists for clear, consensus-based definitions to advance the understanding and treatment of NOE.

Purpose of the Study:

  • To establish consensus definitions for necrotising otitis externa (NOE).
  • To facilitate accurate diagnosis and exclusion of NOE in clinical settings.
  • To expedite high-quality research into this neglected condition.

Main Methods:

  • Systematic literature review.
  • Five iterative rounds of Delphi consultation with expert clinicians.
  • Analysis of results by an expert panel and endorsement by national specialty bodies.

Main Results:

  • Consensus definitions and statements for NOE were achieved in the fifth round of consultation.
  • Agreement criteria included at least 70% agreement and less than 15% disagreement.
  • Seventy-four UK clinicians from ENT, Infection, and Radiology participated.

Conclusions:

  • The developed definitions provide practical guidance for NOE clinical practice and research.
  • This work represents a foundational step; further validation and testing of definitions are planned.
  • The consensus definitions aim to improve the management and study of necrotising otitis externa.