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Author Spotlight: A Model to Study the Systemic and Local Dynamics of CD8+ T Cells During LN Metastasis
Published on: January 26, 2024
[A Case of Long-Term Survival of Breast Cancer with Extra-Regional Lymph Node Metastases]
Takahiro Suzuki1, Akimasa Nishimura, Akiko Igawa
1Dept. of Gastroenterological Surgery, Hirosaki University Graduate School of Medicine.
Abstract:
We present the case of a 65-year-old woman who presented with nipple retraction of her left breast. The patient has a family history of breast cancer. She was diagnosed with bilateral breast cancer with left axillary, cervical, and mediastinal lymph node metastasis(right breast cancer, cT1cN0M0, cStage Ⅰ, Luminal A-like, left breast cancer, cT2N3bM1[LYM], Stage Ⅳ, triple negative type). She was recommended chemotherapy due to her inoperable advanced-stage breast cancer. After 6 courses of administration of AC chemotherapy(doxorubicin and cyclophosphamide)and 5 courses of tri-weekly docetaxel chemotherapy, shrinkage of the primary lesion and disappearance of each swollen lymph node were observed via computed tomography. Surgery was performed 11 weeks post-chemotherapy. Residual lesions, less than 10 mm in size in both the left and right breast masses, were observed. No lymph node metastasis was observed. Four years later, no signs of recurrence have been noted.

