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Assessment of Vascular Function in Patients With Chronic Kidney Disease
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Assessment of Vascular Function in Patients With Chronic Kidney Disease

Published on: June 16, 2014

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Diagnostic value of visceral adiposity index in chronic kidney disease: a meta-analysis

Tingting Fang1, Qiuling Zhang2, Yanmei Wang3

  • 1School of Public Health, Hangzhou Normal University, Hangzhou, 311121, Zhejiang Province, China.

Acta Diabetologica
|February 22, 2023
PubMed

Insights

The visceral adiposity index (VAI) shows promise as a tool for predicting chronic kidney disease (CKD). This meta-analysis suggests VAI can aid in CKD detection, though further validation is recommended.

Area of Science:

  • Nephrology and Endocrinology
  • Diagnostic Accuracy Studies

Background:

  • Inconsistencies exist regarding the predictive value of the visceral adiposity index (VAI) for chronic kidney disease (CKD).
  • The diagnostic utility of VAI for CKD requires further clarification.

Approach:

  • A systematic meta-analysis was conducted, searching PubMed, Embase, Web of Science, and Cochrane databases up to November 2022.
  • Seven studies with 65,504 participants were included, with quality assessed using QUADAS-2.
  • Statistical analyses, including heterogeneity and publication bias assessments, were performed using Review Manager, Meta-disc, and STATA.

Key Points:

  • The pooled analysis yielded a sensitivity of 0.67, specificity of 0.75, and an AUC of 0.77.
  • The positive likelihood ratio was 2.7 and the negative likelihood ratio was 0.44.
  • Mean age of participants was identified as a potential source of heterogeneity.

Conclusions:

  • The visceral adiposity index (VAI) demonstrates potential as a valuable biomarker for predicting and detecting chronic kidney disease (CKD).
  • Further research is warranted to validate these findings and establish VAI's role in clinical practice.
Abstract

Keywords:
Chronic kidney disease (CKD)Meta-analysisVisceral adiposity index (VAI)

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