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Updated: Aug 9, 2025

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Published on: June 10, 2025
Heart Failure and Multimorbidity in Asia
Nathalie Ang1, Chanchal Chandramouli2,3, Kelvin Yiu4,5
1Saw Swee Hock School of Public Health, The National University of Singapore (NUS), 12 Science Drive 2, Singapore, #10-01117549, Singapore.
Purpose Of The Review:
Multimorbidity, the presence of two or more comorbidities, is common in patients with heart failure (HF) and worsens clinical outcomes. In Asia, multimorbidity has become the norm rather than the exception. Therefore, we evaluated the burden and unique patterns of comorbidities in Asian patients with HF.
Recent Findings:
Asian patients with HF are almost a decade younger than Western Europe and North American patients. However, over two in three patients have multimorbidity. Comorbidities usually cluster due to the close and complex links between chronic medical conditions. Elucidating these links may guide public health policies to address risk factors. In Asia, barriers in treating comorbidities at the patient, healthcare system and national level hamper preventative efforts. Asian patients with HF are younger yet have a higher burden of comorbidities than Western patients. A better understanding of the unique co-occurrence of medical conditions in Asia can improve the prevention and treatment of HF.
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