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Humira: the first $20 billion drug
Jason B Gibbons1, Micaela Laber, Charles L Bennett
1Department of Health Policy and Management, Johns Hopkins Bloomberg School of Public Health, 615 N Wolfe St, Baltimore, MD 21205.
The American Journal of Managed Care
|February 22, 2023
Summary
AbbVie
Area of Science:
- Pharmaceutical market analysis
- Healthcare policy and economics
Background:
- AbbVie's adalimumab (Humira) is the world's top-selling drug.
- Government concerns over Humira spending led to a 2019 investigation into AbbVie's practices.
Approach:
- Review of US House Committee on Oversight and Accountability reports.
- Analysis of policy debates surrounding pharmaceutical pricing and market exclusivity.
Key Points:
- Incumbent manufacturers utilize strategies like patent thickets, evergreening, and Paragraph IV settlements to block competition.
- These tactics, including product hopping and linking executive compensation to sales, are prevalent in the pharmaceutical industry.
- Such practices may hinder a competitive market for essential medicines.
Conclusions:
- Legal and policy reforms are needed to curb anticompetitive behaviors in the pharmaceutical sector.
- Increased competition, particularly through biosimilars, can improve access to therapeutic options.
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