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Ocular Therapeutic Delivery and Advanced Tissue Retrieval in Adult Rats

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Published on: May 23, 2025

Topical Ocular Therapeutics in Small Animals.

Elizabeth M James-Jenks¹, Chantale L Pinard¹

¹Department of Clinical Studies, University of Guelph, Ontario Veterinary College, 50 Stone Road East, Guelph, Ontario N1G 2W1, Canada.

The Veterinary Clinics of North America. Small Animal Practice

|February 22, 2023

Summary

This review covers topical ophthalmic medications, detailing their absorption, systemic effects, and pharmacology. Understanding ocular pharmacokinetics is key for managing animal eye diseases effectively.

Keywords:

Anti-inflammatories Antiglaucoma medications Antimicrobials Lacrostimulants Topical ocular therapeutics

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Area of Science:

Veterinary Ophthalmology
Pharmacology

Background:

Topical ophthalmic medications are frequently used in veterinary medicine.
Understanding their absorption and potential systemic effects is crucial for safe and effective treatment.

Purpose of the Study:

To review the administration of common topical ophthalmic drugs.
To discuss factors influencing drug absorption and potential systemic effects.
To provide insights into the pharmacology, indications, and adverse effects of these medications.

Main Methods:

Literature review of common topical ophthalmic preparations.
Analysis of factors affecting ocular drug absorption.
Discussion of pharmacological properties and clinical use.

Main Results:

Ocular drug absorption is influenced by formulation composition.
Systemic absorption can lead to adverse effects.
Specific medications are reviewed for their pharmacology, indications, and side effects.

Conclusions:

Knowledge of topical ocular pharmacokinetics is essential for veterinary ophthalmology.
Informed administration of ophthalmic drugs improves patient outcomes and safety.