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Patterns of acute pediatric intoxication in Aljouf Province, KSA
Mahrous A Ibrahim1,2, Khaled N Alfahd3, Abdulaziz T Alruwaili3
1Forensic Medicine and Clinical Toxicology, College of Medicine, Jouf University, Sakaka, KSA.
Insights
Childhood intoxication in Aljouf, KSA, primarily affects young children, with pharmaceutical drugs being the leading cause. Enhancing caregiver awareness and prevention strategies are crucial to reduce pediatric intoxication rates.
Area of Science:
- Pediatric Toxicology
- Public Health
- Epidemiology
Background:
- Childhood intoxication is a significant global health concern, contributing to morbidity and mortality.
- Preventable causes of childhood poisoning necessitate understanding local patterns and outcomes.
Purpose of the Study:
- To investigate the patterns and outcomes of acute pediatric intoxication in Aljouf, Saudi Arabia.
- To identify key demographic and exposure-related factors associated with pediatric intoxication.
Main Methods:
- A retrospective descriptive study analyzed 540 cases of acute intoxication in children under 18 years (2015-2021).
- Data included demographics, exposure details, clinical presentation, treatment, and outcomes.
- Logistic regression identified predictors of accidental intoxication.
Main Results:
- The majority of cases (79%) involved children aged 1 to <6 years. Pharmaceutical drugs accounted for 41% of poisonings.
- Most children (84%) were asymptomatic on admission; gastrointestinal symptoms were most common in symptomatic cases.
- Complete recovery was observed in 43% of cases, with 29.4% discharged against medical advice. Age and urban/rural residence predicted accidental intoxication.
Conclusions:
- Acute pediatric intoxication poses a significant public health challenge in Aljouf, KSA.
- Increased caregiver awareness of toxic agents and risk factors is essential.
- Implementing effective prevention strategies is vital to reduce the incidence of pediatric intoxication.
Objectives:
Although childhood intoxication is avoidable, it remains a leading cause of morbidity and mortality in both developing and developed countries. The aim of this study was to assess the patterns and outcomes of acute pediatric intoxication in Aljouf, KSA.
Methods:
A retrospective record-based descriptive study was conducted at the Prince Mutaib bin Abdulaziz hospital, and the Maternity and Children's hospital in Aljouf, KSA. All cases of acute intoxication in children younger than 18 years of age from January 1, 2015 to December 31, 2021 were included. Data analysis included demographic characteristics; year and month of intoxication; place, time, form, and route of toxic agent exposure; manner of intoxication; toxic agent/agents involved; intoxicated child's status upon arrival at the hospital; clinical presentation; treatment; admission history; and outcome.
Results:
A total of 540 cases were reported. Most (79%) acutely intoxicated children were in 1 to <6 years of age. The highest frequency of reported acute pediatric intoxication was 23.9% in 2017. Pharmaceutical drugs were responsible for most reported cases (41%). Most children were asymptomatic (84%) at the time of admission. Among symptomatic children, GIT clinical manifestations were the most reported symptoms. Forty percent of the children were admitted to the inpatient ward. Interestingly, 29.4% were discharged against medical advice. Approximately 43% showed complete recovery. The logistic regression model of predictors of accidental intoxication indicated that only age and residence in urban vs rural areas had a statistically significant relationship.
Conclusions:
Acute pediatric intoxication is a problem in Aljouf, KSA. Caregivers' awareness of the potentially hazardous toxic agents and risk factors for pediatric intoxication should be enhanced, and effective prevention strategies should be implemented to decrease the incidence of pediatric intoxication.
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