Related Experiment Video
Updated: Aug 9, 2025

06:53
Modeling Primary Bone Tumors and Bone Metastasis with Solid Tumor Graft Implantation into Bone
Published on: September 9, 2020
2.8K
Malignant Transformation in Ollier's Disease: A Novel Stem for a Tibial Megaprosthesis
1Department of Orthopedics, University of Maryland Medical Center, Baltimore, USA.
Cureus
|February 24, 2023
Abstract:
Ollier's disease is a rare syndrome characterized by multiple enchondromas with the potential for malignant transformation. The treatment for secondary chondrosarcoma is surgical resection, which can be a morbid procedure depending on the location and size of the tumor. We present a successful limb salvage in which the majority of the tibia was removed and replaced with a megaprosthesis. The complex reconstruction in this case required the use of a novel uncemented stem.
Keywords:
chondrosarcomaenchondromaendoprosthesismalignant transformationmegaprosthesisollier’s diseasetibial reconstruction
