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Related Concept Videos

Antimicrobial Effectiveness01:28

Antimicrobial Effectiveness

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The effectiveness of antimicrobial agents depends on various factors influencing their ability to eliminate microbial populations. Larger microbial populations require more time for complete eradication, emphasizing the importance of population size analysis when evaluating antimicrobial efficacy.Microbial resistance to antimicrobial agents varies significantly. Highly resilient microorganisms include endospores, gram-negative bacteria, and non-enveloped viruses, while prions are exceptionally...
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The high insolubility of some precipitates can result in an unfavorable relative supersaturation. This can lead to colloidal particles with a large surface-to-mass ratio, where adsorption is promoted. For instance, in the precipitation of silver chloride, silver ions are adsorbed on the surface of the colloidal particles, forming a primary layer. This layer attracts ions of opposite charge (such as nitrate ions), forming a diffuse secondary layer of adsorbed ions. This electric double layer...
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The skin and mucous membranes serve as the primary line of defense against pathogens by providing both physical and chemical protection. These barriers are essential in preventing the entry and establishment of microbes, thereby maintaining the integrity of the host.
The outer layer of the skin, the epidermis, is a robust barrier comprising layers of closely packed keratinized cells. This dense arrangement prevents microbes from penetrating the body. The periodic shedding of epidermal cells...
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Antimicrobial Polymeric Surfaces Using Embedded Silver Nanoparticles.

Pooja Sharma1,2, Luisa Fialho3,4, Nuno Miguel Figueiredo1

  • 1CEMMPRE, Mechanical Engineering Department, University of Coimbra, 3030-788 Coimbra, Portugal.

Antibiotics (Basel, Switzerland)
|February 25, 2023
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Summary
This summary is machine-generated.

Antimicrobial surfaces embedding silver nanoparticles (Ag NPs) show significant potential in preventing pathogen transmission. This cost-effective, scalable method enhances polymer surfaces, inhibiting bacterial growth on contact.

Keywords:
antimicrobial activityglass transition temperaturepolycarbonatesilver nanoparticlesthermal embedding

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Area of Science:

  • Materials Science
  • Nanotechnology
  • Microbiology

Background:

  • Pathogens transmit diseases via contaminated surfaces, necessitating effective antimicrobial solutions.
  • Antimicrobial surfaces offer a promising strategy to mitigate pathogen spread.

Purpose of the Study:

  • To develop and evaluate antimicrobial polymer surfaces embedded with silver nanoparticles (Ag NPs).
  • To assess the antibacterial efficacy of Ag NP-embedded polycarbonate (PC) against common bacteria.

Main Methods:

  • Sputter deposition of a silver nanolayer onto a polycarbonate (PC) substrate.
  • Two-step thermal annealing process to promote Ag NP diffusion, growth, and surface embedding.
  • Evaluation of antibacterial capacity against Gram-positive and Gram-negative bacteria.

Main Results:

  • Successful embedding of silver nanoparticles (Ag NPs) into the PC surface confirmed by height variation after annealing.
  • Ag NP-embedded PC surfaces demonstrated significant inhibition of both Gram-positive and Gram-negative bacterial growth.
  • The surface engineering process proved to be cost-effective and highly scalable.

Conclusions:

  • Embedding antimicrobial Ag NPs into polymer surfaces is an effective strategy to create self-disinfecting materials.
  • This method offers a scalable and economical approach to reduce pathogen transmission from surfaces.
  • The developed antimicrobial surfaces hold potential for widespread application in public health and hygiene.