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Updated: Aug 12, 2026

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[Hemostatic homeostasis following radio-synovectomy in rheumatoid arthritis]
Abstract:
Platelet functional activity, plasma coagulation and fibrinolysis were studied in patients with rheumatoid arthritis (RA) against a background of various therapeutic modalities. Therapy with non-steroid anti-inflammatory agents resulted in an increase in platelet and plasma coagulating activity and inhibition of fibrinolysis. An insignificant rise of disaggregation of platelet aggregates was noted 2 weeks after intraarticular administration of 198Au against a background of therapy with non-steroid anti-inflammatory agents. Mydocalm incorporated in a dose of 1-2 mg/kg in the therapeutic scheme did not change significantly blood coagulation indices.
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