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Microfluidic Chip Fabrication and Method to Detect Influenza
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Microfluidics for COVID-19: From Current Work to Future Perspective.

Qi Li1, Xingchen Zhou2, Qian Wang1

  • 1Department of Pharmacy, Xiangya School of Pharmaceutical Sciences, Central South University, Changsha 410017, China.

Biosensors
|February 25, 2023
PubMed
Summary
This summary is machine-generated.

Microfluidic technology offers rapid, cost-effective point-of-care testing (POCT) for COVID-19 diagnosis. This review explores microfluidic platforms and assays to aid in controlling the pandemic.

Keywords:
COVID-19immunoassaysmicrofluidicmolecular assays

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Area of Science:

  • Biomedical Engineering
  • Diagnostic Technologies
  • Public Health

Background:

  • The COVID-19 pandemic necessitates rapid, accessible diagnostic tools.
  • Point-of-care testing (POCT) is crucial for controlling disease transmission.
  • Microfluidics offers advantages like miniaturization and low sample requirements for POCT.

Purpose of the Study:

  • To review microfluidic-based POCT devices for COVID-19 diagnosis.
  • To summarize various microfluidic diagnostic assays.
  • To present future perspectives on microfluidic diagnostic development.

Main Methods:

  • Review of microfluidic platforms driven by different forces (paper-based, centrifugal, optical, digital).
  • Summary of microfluidic immunoassays (e.g., ELISA) and molecular assays (e.g., PCR) for COVID-19.
  • Analysis of challenges and future directions in microfluidic device design.

Main Results:

  • Microfluidic technology is vital for developing advanced POCT devices.
  • Diverse microfluidic platforms and assays are available for COVID-19 detection.
  • Specific platforms like paper-based and digital microfluidics show promise.

Conclusions:

  • Microfluidic diagnostics are essential for effective COVID-19 management.
  • Further development in microfluidic device design is needed.
  • This review provides insights for future microfluidic diagnostic innovations.