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High-Risk Neuroblastoma: A Surgical Perspective
Jillian C Jacobson1,2, Rachael A Clark1,2, Dai H Chung1,2
1Department of Pediatric Surgery, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
Children (Basel, Switzerland)
|February 25, 2023
Summary
High-risk neuroblastoma treatment involves surgery. This review details optimal surgical timing, extent, and techniques for managing this complex pediatric cancer.
Area of Science:
- Pediatric Oncology
- Surgical Oncology
Background:
- High-risk neuroblastoma necessitates comprehensive multimodal therapy.
- Surgical resection is crucial for achieving local tumor control.
Purpose of the Study:
- To review optimal surgical strategies for high-risk neuroblastoma.
- To guide surgeons on resection timing, extent, and techniques.
Main Methods:
- Literature review focusing on surgical management of neuroblastoma.
- Analysis of image-defined risk factors impacting surgical planning.
Main Results:
- Optimal timing and extent of resection are critical for outcomes.
- Image-defined risk factors influence surgical approach and success.
- Specific techniques improve tumor resection in various anatomical locations.
Conclusions:
- Surgeons require in-depth knowledge of neuroblastoma pathology for effective treatment.
- Tailored surgical approaches enhance local control in high-risk neuroblastoma.
