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Cognitive development continues throughout adulthood, undergoing significant shifts across early, middle, and late stages. Individual transition occurs from adolescent idealism to pragmatic and adaptable thinking in early adulthood. During this period, individuals learn to integrate personal beliefs with the recognition that other perspectives are equally valid. Exposure to the complexities of modern society, diverse experiences, and higher education contribute to this adaptive thought process,...
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Personalized Computerized Training for Cognitive Dysfunction after COVID-19: A Before-and-After Feasibility Pilot

Jon Andoni Duñabeitia1,2, Francisco Mera3, Óscar Baro4

  • 1AcqVA Aurora Center, Department of Languages and Culture, UiT the Arctic University of Norway, 9019 Tromsø, Norway.

International Journal of Environmental Research and Public Health
|February 25, 2023
PubMed
Summary
This summary is machine-generated.

Personalized computerized cognitive training (CCT) improved cognitive function in individuals with post-acute sequelae of COVID-19 (PASC). This 8-week home-based intervention showed significant gains across multiple cognitive domains.

Keywords:
Long COVIDcomputerized cognitive trainingdigital therapeuticspandemicspost-acute sequelae of COVID-19

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Area of Science:

  • Neuroscience
  • Rehabilitation Medicine
  • Infectious Disease Research

Background:

  • Post-acute sequelae of COVID-19 (PASC) often include persistent cognitive dysfunction.
  • Cognitive impairment significantly impacts quality of life for individuals with PASC.
  • There is a need for accessible interventions to address cognitive deficits in PASC.

Purpose of the Study:

  • To assess the feasibility of a personalized computerized cognitive training (CCT) intervention for PASC.
  • To evaluate the potential benefits of CCT on cognitive function in PASC patients.
  • To explore factors influencing CCT effectiveness, including age and training duration.

Main Methods:

  • A pilot study involving 73 adults with self-reported cognitive dysfunction post-COVID-19.
  • An 8-week self-administered, home-based personalized CCT program using a dedicated application.
  • Cognitive function was assessed at baseline and after the 8-week intervention across five domains.

Main Results:

  • Participants demonstrated significant improvements in attention, memory, coordination, perception, and reasoning post-CCT.
  • The magnitude of cognitive score increase was substantial across all assessed domains.
  • Improvements were observed irrespective of age, training time, or time since COVID-19 infection.

Conclusions:

  • Self-administered, gamified CCT is a feasible and potentially effective intervention for ameliorating cognitive dysfunction in individuals with PASC.
  • Computerized cognitive training offers a promising avenue for PASC cognitive rehabilitation.
  • Further research is warranted to optimize CCT protocols for long-term cognitive recovery.