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Hormonal Regulation of the Menstrual Cycle01:22

Hormonal Regulation of the Menstrual Cycle

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The ovarian cycle regulates endometrial changes throughout a single menstrual cycle via the coordinated action of gonadotrophin-releasing hormone (GnRH) and gonadotrophins.
At puberty, GnRH begins a pulsatile release pattern, which triggers the anterior pituitary gland to secrete follicle-stimulating hormone (FSH) and luteinizing hormone (LH). The frequency and amplitude of GnRH pulses vary across the menstrual cycle, with faster pulses favoring LH release and slower pulses favoring FSH...
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The Menstrual Cycle01:19

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The menstrual cycle is a recurrent sequence of changes in the uterine endometrium, specifically its functional layer, the stratum functionalis. This cycle prepares the uterus for potential pregnancy. This cycle typically spans 21–35 days, averaging 28 days, and aligns with the ovarian cycle, regulated by fluctuating levels of ovarian hormones, primarily estrogen and progesterone.
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Menses Phase

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The uterine cycle begins with the menstrual phase, which is considered day one of the cycle and typically lasts about five days. This phase is characterized by the degeneration and shedding of the stratum functionalis, the functional layer of the endometrium.
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Exercise and Cardiovascular Response01:20

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Exercise significantly impacts cardiovascular response, which is crucial for understanding patient health and designing effective treatment plans.
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Hormonal Control of the Ovarian Cycle01:30

Hormonal Control of the Ovarian Cycle

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The ovarian cycle is meticulously regulated by the hypothalamic-pituitary-gonadal axis. This cycle orchestrates the release of a mature oocyte, essential for reproduction.
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Disorders of the Female Reproductive System

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The female reproductive system can be affected by several disorders, including Premenstrual Syndrome (PMS), Premenstrual Dysphoric Disorder (PMDD), endometriosis, and various forms of cancer. PMS and PMDD are cyclical conditions that cause physical and emotional distress, with symptoms that include edema, mood swings, and food cravings. PMDD is a more severe form of PMS characterized by increased symptom severity that peaks during the luteal phase and tends to improve or resolve shortly after...
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An Inertial Measurement Unit Based Method to Estimate Hip and Knee Joint Kinematics in Team Sport Athletes on the Field
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Menstrual Cycle and Sport Injuries: A Systematic Review.

Núria Martínez-Fortuny1, Alejandra Alonso-Calvete1,2, Iria Da Cuña-Carrera1,3

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International Journal of Environmental Research and Public Health
|February 25, 2023
PubMed
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Female athletes face increased injury risk due to menstrual cycle hormonal fluctuations. The ovulatory phase, marked by peak estradiol, is linked to greater laxity and neuromuscular changes, elevating injury predisposition.

Keywords:
athletesmenstrual cyclesportssports injuries

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Area of Science:

  • Sports Medicine
  • Endocrinology
  • Biomechanical Analysis

Background:

  • Female athletic participation and sports-related injuries are rising.
  • Hormonal factors, particularly the menstrual cycle, are suspected contributors to injury risk in female athletes.
  • A definitive causal link between the menstrual cycle and injury incidence remains to be established.

Approach:

  • A systematic literature review was conducted in January 2022.
  • Searches were performed across major scientific databases: PubMed, Medline, Scopus, Web of Science, and Sport Discus.
  • Eight studies met the inclusion criteria from an initial pool of 138 articles.

Key Points:

  • Peak estradiol levels during the ovulatory phase correlate with increased joint laxity.
  • Elevated estradiol is associated with decreased neuromuscular control and altered strength.
  • These physiological changes during the menstrual cycle may predispose female athletes to injury.

Conclusions:

  • Hormonal fluctuations during the menstrual cycle significantly impact physiological parameters relevant to injury risk.
  • Changes in laxity, strength, body temperature, and neuromuscular control are observed.
  • Female athletes' continuous adaptation to hormonal variations may lead to an elevated risk of sports-related injuries.