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Benign Paroxysmal Positional Vertigo Is Associated with an Increased Risk for Migraine Diagnosis: A Nationwide

I-An Shih1,2,3, Chung-Y Hsu4, Tsai-Chung Li1,5

  • 1Department of Public Health, College of Public Health, China Medical University, Taichung 404327, Taiwan.

International Journal of Environmental Research and Public Health
|February 25, 2023
PubMed

Insights

Patients with benign paroxysmal positional vertigo (BPPV) have a significantly higher risk of developing migraine. This study found BPPV is linked to a nearly threefold increased risk of migraine diagnosis.

Area of Science:

  • Neurology
  • Epidemiology

Background:

  • Previous research suggests a link between migraine and benign paroxysmal positional vertigo (BPPV).
  • The directionality of this association requires further investigation.

Purpose of the Study:

  • To investigate the risk of developing migraine in patients previously diagnosed with benign paroxysmal positional vertigo (BPPV).

Main Methods:

  • A cohort study utilized the Taiwan National Health Insurance Research Database.
  • Patients under 45 with BPPV (2000-2009) were compared to a matched control group without BPPV or migraine.
  • Cox proportional hazards regression analyzed migraine risk, adjusting for age, sex, and comorbidities.

Main Results:

  • 117 out of 1386 participants with BPPV developed migraine.
  • 146 out of 5544 participants without BPPV developed migraine.
  • Benign paroxysmal positional vertigo (BPPV) was associated with a 2.96-fold increased risk of migraine (aHR: 2.96, 95% CI: 2.30-3.80, p < 0.001).

Conclusions:

  • Benign paroxysmal positional vertigo (BPPV) is a significant risk factor for developing migraine.
  • This finding highlights a potential neurological connection between BPPV and migraine.
Keywords:
benign paroxysmal positional vertigocohort studymigraine

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