Lanthanides-Substituted Hydroxyapatite for Biomedical Applications

Area of Science:

• Biomaterials Science
• Nanotechnology
• Biomedical Engineering

Background:

• Growing demand for advanced biomaterials in regenerative medicine and diagnostics.
• Hydroxyapatite (HAp) shows promise but lacks mechanical strength and antimicrobial activity.
• Lanthanides are underutilized elements with significant biomedical potential.

Purpose of the Study:

• To review the biological benefits of lanthanides.
• To explore how lanthanide incorporation into HAp nanoparticles (HAp NPs) affects their properties.
• To present applications of lanthanide-substituted HAp NPs for potential biomedical uses.

Main Methods:

• Literature review focusing on lanthanide-substituted HAp.
• Analysis of how lanthanide doping modifies HAp morphology and physical characteristics.
• Compilation of current and potential applications of these modified nanoparticles.

Main Results:

• Lanthanide doping can enhance HAp's mechanical and antimicrobial properties.
• Incorporation of lanthanides alters HAp NPs' structure and physical attributes.
• Lanthanide-substituted HAp NPs show promise in various biomedical applications.

Conclusions:

• Lanthanide-substituted HAp NPs present a promising avenue for improved regenerative therapies and antimicrobial treatments.
• Further investigation into safe and effective lanthanide substitution percentages is crucial.
• This review highlights the potential of lanthanides in HAp-based biomaterials for diverse biomedical applications.