Related Experiment Video
Updated: Aug 9, 2025

Lumped-Parameter and Finite Element Modeling of Heart Failure with Preserved Ejection Fraction
Published on: February 13, 2021
Hemodynamic Characteristics of Cardiovascular System in Simulated Zero and Partial Gravities Based on CFD Modeling
Lei Sun1,2, Lijie Ding1,3, Lei Li4
1Laboratory of Virtual Reality and Simulation Technology, Shandong Sport University, Jinan 250102, China.
Abstract:
Zero and partial gravities (ZPG) increase cardiovascular risk, while the corresponding theoretical foundation remains uncertain. In the article, the ZPG were generated through a rotating frame with two degrees of freedom in combination with the random walk algorithm. A precise 3D geometric configuration of the cardiovascular system was developed, and the Navier-Stokes laminar flow and solid mechanics were used as governing equations for blood flow and the surrounding tissue in the cardiovascular system. The ZPG were designed into governing equations through the volume force term. The computational fluid dynamics' (CFD) simulations in combination with proper boundary conditions were carried out to investigate the influences of ZPG on the distribution of blood flow velocity, pressure, and shear stress in the cardiovascular system. The findings show that as simulated gravity gradually decreases from 0.7 g to 0.5 g to 0.3 g to 0 g, as opposed to normal gravity of 1 g, the maximum values of blood flow velocity, pressure, and shear stress on the walls of the aorta and its ramification significantly increase, which would lead to cardiovascular diseases. The research will lay a theoretical foundation for the comprehension of the ZPG effect on cardiovascular risk and the development of effective prevention and control measures under the circumstance of ZPG.
Related Concept Videos
Typical Model Studies
Modeling and Similitude
Pressure Variation in a Fluid at Rest
When measuring pressure at two different levels within the fluid, the difference in...
Physiological Pharmacokinetic Models: Blood Flow-Limited Versus Diffusion-Limited Models
Pressure of Fluids
Dimensionless Groups in Fluid Mechanics

