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Coated intraocular lenses.

R H Keates1, J Powell, E Blosser

  • 1Department of Ophthalmology, Ohio State University, Columbus 43210.

Ophthalmic Surgery
|September 1, 1987
PubMed
Summary
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Sodium hyaluronate-coated intraocular lenses reduce cell damage compared to uncoated lenses. This coating offers improved adherence, endothelial protection, and intraocular lens manipulation.

Area of Science:

  • Ophthalmology
  • Biomaterials Science
  • Cell Biology

Background:

  • Intraocular lens (IOL) implantation is a common surgical procedure.
  • Protecting the corneal endothelium during cataract surgery is crucial.
  • Current IOLs may cause varying degrees of endothelial cell loss.

Purpose of the Study:

  • To evaluate the efficacy of a sodium hyaluronate coating on intraocular lenses.
  • To assess the impact of this coating on endothelial cell damage.
  • To explore potential benefits in lens handling and adherence.

Main Methods:

  • An intraocular lens with a bonded sodium hyaluronate coating was prepared.
  • The coated lens was compared against an uncoated intraocular lens.
  • Cell damage was quantified and compared between the two groups.

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Main Results:

  • The sodium hyaluronate-coated intraocular lens demonstrated significantly less cell damage.
  • The coated lens exhibited enhanced adherence to viscoelastic materials.
  • Improved endothelial protection and potentially better intraocular manipulation were observed.

Conclusions:

  • Sodium hyaluronate coating represents a novel approach to protect ocular tissues during IOL implantation.
  • This coating offers significant advantages in reducing cell damage and improving surgical handling.
  • This is the first report detailing the use of a sodium hyaluronate-coated IOL for preventing cell damage.