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Generation of a Mouse Spontaneous Autoimmune Thyroiditis Model
Published on: March 17, 2023
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Covid-induced thyroiditis
Tahir Ghaffar1, Bakht Babar1, Mian Sameer Ahmad1
1Department of Diabetes and Endocrinology, Medical Teaching Institute, Hayatabad Medical Complex, Peshawar.
JPMA. the Journal of the Pakistan Medical Association
|February 26, 2023
Summary
COVID-19 can cause thyroiditis, leading to hyperthyroidism. This case study shows a patient recovered fully with anti-inflammatory treatment after experiencing thyrotoxic symptoms post-COVID-19 infection.
Area of Science:
- Endocrinology
- Virology
- Immunology
Background:
- Thyroiditis is an emerging manifestation of COVID-19.
- COVID-19-associated thyroiditis often presents with thyrotoxicosis.
- Diagnosis relies on thyroid function tests and inflammatory markers.
Observation:
- A 39-year-old female presented with thyrotoxicosis symptoms weeks after COVID-19 recovery.
- Symptoms included neck pain, odynophagia, and intermittent fever.
- No prior history of endocrine or significant medical conditions was noted.
Findings:
- Thyroid function tests (TFTs) indicated hyperthyroidism with elevated T3 and T4, and suppressed TSH.
- Thyroid scan showed decreased uptake, and elevated ESR (115) suggested inflammation.
- Treatment involved NSAIDs, steroids, and a beta-blocker.
Implications:
- This case highlights thyroiditis as a potential post-COVID-19 complication.
- Prompt diagnosis and appropriate treatment led to symptom resolution and normalized TFTs.
- Further research is warranted to understand the pathophysiology and long-term effects of COVID-19-associated thyroiditis.
Keywords:
Covid-19, thyroiditis.Related Concept Videos
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