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Related Concept Videos

The Thyroid Gland01:23

The Thyroid Gland

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The thyroid gland is a small, butterfly-shaped gland located in the neck and covers the anterior surface of the trachea. The gland has two lateral lobes connected by a thin tissue mass called the isthmus. Internally, each lobe comprises many small spherical structures known as thyroid follicles, surrounded by a network of blood vessels.
The follicles have a central cavity lined by simple cuboidal to squamous epithelial cells called follicular cells. These cells produce the glycoprotein...
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Primary Lymphoid Organs01:16

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Primary lymphoid organs are pivotal in the formation, development, and maturation of lymphocytes, the white blood cells that serve as the backbone of our immune system. This crucial function underscores their fundamental role in maintaining our overall health and immunity. The two primary lymphoid organs of prime importance are the red bone marrow and the thymus.
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Secondary Lymphoid Organs01:15

Secondary Lymphoid Organs

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Secondary organs, including lymph nodes, the spleen, and mucosa-associated lymphoid tissue (MALT), work harmoniously to protect us from disease and infection.
The spleen is a vital organ in the lymphatic system, nestled in the upper left side of the abdomen. It is composed of two primary regions: the red pulp and the white pulp, each having distinct functions. The red pulp performs a significant role in blood filtration. It efficiently purges the blood of old or damaged red blood cells and...
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Synthesis and Regulation of Thyroid Hormones01:20

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Low blood levels of the thyroid hormones — triiodothyronine (T3) and thyroxine (T4) — signal the hypothalamus to release the thyrotropin-releasing hormone (TRH). TRH then reaches the pituitary gland and stimulates the release of thyroid-stimulating hormone(TSH) into the bloodstream.
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Updated: Aug 8, 2025

Transoral Robotic Total Thyroidectomy and Bilateral Central Regional Lymph Node Dissection for Papillary Thyroid Carcinoma
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Transoral Robotic Total Thyroidectomy and Bilateral Central Regional Lymph Node Dissection for Papillary Thyroid Carcinoma

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Primary thyroid lymphoma: A single-center experience.

Jin Seok Lee1, Su-Jin Shin2, Hyeok Jun Yun1

  • 1Department of Surgery, Thyroid Cancer Center, Gangnam Severance Hospital, Institute of Refractory Thyroid Cancer, Yonsei University College of Medicine, Seoul, Republic of Korea.

Frontiers in Endocrinology
|February 27, 2023
PubMed
Summary
This summary is machine-generated.

Primary thyroid lymphoma (PTL) is a rare cancer. This study identified clinical, biochemical, and pathological features of PTL in ten patients, predominantly non-Hodgkin B-cell lymphomas, emphasizing individualized treatment.

Keywords:
Hashimoto’s thyroiditisHodgkin’s lymphomafine needle aspiratenon-Hogdkin’s lymphomathyroid lymphoma

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Area of Science:

  • Oncology
  • Hematology
  • Pathology

Background:

  • Primary thyroid lymphoma (PTL) is a rare malignancy, comprising 5% of thyroid cancers and <2% of lymphomas.
  • PTLs are predominantly non-Hodgkin B-cell lymphomas, though Hodgkin's lymphoma can occur.
  • Understanding PTL's features is crucial for diagnosis and management.

Purpose of the Study:

  • To identify the clinical, biochemical, and pathological characteristics of primary thyroid lymphomas.
  • To contribute to the understanding of this rare entity.

Main Methods:

  • Retrospective analysis of 10 PTL patients treated between January 2008 and December 2020.
  • Inclusion of clinical, biochemical, and pathological data.
  • Biopsies (fine needle aspiration, excisional, surgical) and treatment modalities were assessed.

Main Results:

  • Ten patients (9 female, 1 male; median age 62) were analyzed.
  • All 10 cases were non-Hodgkin B-cell lymphomas: 6 diffuse large B-cell lymphoma, 3 mucosa-associated lymphoid tissue lymphoma, 1 Burkitt lymphoma.
  • Treatment varied, including chemotherapy, chemoradiation, radiation therapy, and surgery.

Conclusions:

  • Primary thyroid lymphoma is a rare condition requiring clinical awareness.
  • Evaluation and treatment should be individualized for each PTL patient.
  • Further research may elucidate optimal management strategies.