Related Experiment Video

Updated: Aug 14, 2026

5/6th Nephrectomy in Combination with High Salt Diet and Nitric Oxide Synthase Inhibition to Induce Chronic Kidney Disease in the Lewis Rat
08:50

5/6th Nephrectomy in Combination with High Salt Diet and Nitric Oxide Synthase Inhibition to Induce Chronic Kidney Disease in the Lewis Rat

Published on: July 3, 2013

Reflux nephropathy

J Hodson

    The Medical Clinics of North America
    |November 1, 1978
    PubMed

    Insights

    Reflux nephropathy, a common kidney disease in young females, lacks sufficient research and early detection methods. Early diagnosis in children is crucial to prevent severe forms and reduce long-term costs.

    Area of Science:

    • Nephrology
    • Pediatric Kidney Diseases

    Background:

    • Reflux nephropathy affects 1 in 300 white females and is the second most common kidney disease in the young.
    • Significant gaps in knowledge and coordinated research hinder understanding and management of this condition.

    Purpose of the Study:

    • To highlight the critical need for early detection of reflux nephropathy in young children.
    • To emphasize the importance of preventing severe forms of the disease.

    Main Methods:

    • This study is a review of the current understanding and challenges in reflux nephropathy.
    • It identifies the lack of information and coordinated action as key issues.

    Main Results:

    • There is a notable deficiency in data regarding crucial aspects of reflux nephropathy.
    • The financial cost of treating end-stage disease is estimated to be substantial, potentially reaching hundreds of millions annually.

    Conclusions:

    • A coordinated effort is needed to gather more information on reflux nephropathy.
    • Developing early detection methods for young children is paramount to mitigate the disease's impact and associated costs.

    More Related Videos

    Analysis of Nephron Composition and Function in the Adult Zebrafish Kidney08:53

    Analysis of Nephron Composition and Function in the Adult Zebrafish Kidney

    Published on: August 9, 2014

    Mouse Model of Acute to Chronic Kidney Disease Transition Induced by Renal Ischemia/Reperfusion Injury07:02

    Mouse Model of Acute to Chronic Kidney Disease Transition Induced by Renal Ischemia/Reperfusion Injury

    Published on: February 10, 2026

    Related Concept Videos

    Nephrons01:10

    Nephrons

    The kidneys are intricate organs with millions of working units known as nephrons. Each nephron features two major structures: the renal corpuscle, which facilitates blood plasma filtration, and the renal tubule, which handles the glomerular filtrate. Blood supply is directly linked to the nephrons. The renal corpuscle consists of the glomerulus, a capillary network, and the Bowman's capsule, a double-walled epithelial structure that encases the glomerulus. The filtering of blood plasma happens...
    Renal Corpuscle01:20

    Renal Corpuscle

    The glomerulus and Bowman's capsule are two essential components of the nephron, which is the functional unit of the kidney. These microscopic structures play a critical role in the process of blood filtration to produce urine.
    Glomerulus: Structure and Function
    The glomerulus is a tiny, intricate network of capillaries located at the beginning of the nephron. It's enveloped by the Bowman's capsule and receives its blood supply from an afferent arteriole, which divides into numerous capillaries...
    Acute Pyelonephritis I: Introduction01:27

    Acute Pyelonephritis I: Introduction

    Pyelonephritis is a bacterial infection that primarily affects the renal parenchyma and collecting system, including the renal pelvis, tubules, and interstitial tissue of one or both kidneys. It can be classified as either acute—a sudden, severe infection—or chronic, which refers to long-term or recurrent kidney infections.The primary cause of acute pyelonephritis (APN) is bacterial infection, with Escherichia coli accounting for approximately 70-80% of cases. Other bacteria, such as Proteus,...
    Nephrotic Syndrome I : Introduction01:24

    Nephrotic Syndrome I : Introduction

    Nephrotic Syndrome is a chronic kidney disorder defined by clinical findings such as severe proteinuria, hypoalbuminemia, hyperlipidemia, and edema. These symptoms result from damage to the glomeruli, the kidney’s filtering units, increasing their permeability to proteins.Definition and Meaning:Proteinuria, defined as the loss of more than 3.5 grams of protein per day in adults, is a crucial feature of nephrotic syndrome. This condition is often accompanied by edema, the accumulation of fluid...
    Acute Kidney Injury II: Pathophysiology01:29

    Acute Kidney Injury II: Pathophysiology

    Acute kidney injury (AKI) causes are categorized into three primary categories based on the location of the injury: prerenal, intrarenal (or intrinsic), and postrenal causes. This classification guides clinical management and illustrates how different pathways can impair kidney function.Etiology and Pathophysiology of Acute Kidney Injury1. Prerenal causesEtiology: Prerenal Acute Kidney Injury, the most common type, occurs when reduced blood flow to the kidneys decreases filtration capacity...
    Diabetic Nephropathy01:28

    Diabetic Nephropathy

    Definition Diabetic nephropathy is a chronic kidney complication that results from prolonged hyperglycemia.Prevalence It is the most common cause of chronic kidney disease (CKD) and end-stage renal disease (ESRD) worldwide, affecting up to half of individuals with diabetes.Pathophysiology • Sustained hyperglycemia triggers multiple hemodynamic and metabolic changes in the kidney. • Early in the disease, increased renal blood flow and glomerular hyperfiltration occur due to afferent arteriolar...