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Prevalence and Associated Risk Factors of Anemia Among Hospitalized Children in a Tertiary Level Hospital in Botswana
Aobakwe Betty Siamisang1, Alemayehu M Gezmu1, Jeremy S Slone2
1University of Botswana, Gaborone, Botswana.
Insights
Anemia affects nearly half of children under five in Botswana, with older children showing a lower risk. This study highlights anemia as a significant pediatric health issue in the region.
Area of Science:
- Pediatrics
- Hematology
- Global Health
Background:
- Anemia poses a global health challenge with potential long-term cognitive and behavioral impacts.
- Iron deficiency anemia is a common subtype, particularly concerning in pediatric populations.
Purpose of the Study:
- To determine the prevalence and identify risk factors for anemia in infants and children (6 months to 5 years) in Botswana.
- To assess the severity and type of anemia in the studied pediatric cohort.
Main Methods:
- A cross-sectional study involving 250 pediatric patients admitted to a tertiary hospital in Botswana.
- Anemia was assessed via baseline full blood count, with data collected from medical records and parental interviews.
- Multivariate logistic regression analysis was employed to identify independent predictors of anemia.
Main Results:
- The prevalence of anemia in the pediatric cohort was 42.8%.
- Mild anemia (56.1%) was most common, followed by moderate (39.2%) and severe (4.7%).
- Microcytic anemia, suggestive of iron deficiency, was found in 57% of anemic patients. Age was the sole independent predictor, with children 24 months and older having a 50% reduced risk (OR 0.52).
Conclusions:
- Anemia represents a substantial public health concern within the pediatric population in Botswana.
- The findings underscore the need for targeted interventions to address anemia in young children in this region.
- Age is a critical factor, with younger children being more vulnerable to developing anemia.
Abstract:
Anemia is a global health concern and has been associated with long term cognitive and behavioral adverse effects. A cross sectional study was conducted to determine the prevalence of and risk factors for anemia in infants and children between 6 months to 5 years of age admitted to a tertiary hospital in Botswana. Baseline full blood count of every patient admitted during the study period was assessed to determine if anemia was present. Data were collected from patient's medical inpatient chart, electronic medical record (Integrated Patient Management System (IPMS)), and through interviewing parents and caregivers. Multivariate logistic regression model was used to identify risk factors of anemia. A total of 250 patients were included in the study. Prevalence of anemia in this cohort was 42.8%. There were 145 (58%) males. Of the patients with anemia, 56.1%, 39.2%, and 4.7% had mild, moderate, and severe anemia, respectively. Microcytic anemia consistent with iron deficiency was identified in 61 (57%) patients. Age was the only independent predictor of anemia. Children aged 24 months and more had a 50% lower risk of having anemia than their younger counterparts (odds ratio (OR) 0.52; 95% Confidence Interval (95% CI) 0.30 to 0.89). The findings of this study demonstrate anemia as a serious health concern in the pediatric population in Botswana.
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