[Engineering and process management-based design of Comprehensive Biotechnology Experiment course]

Area of Science:

• Biotechnology
• Biochemical Engineering
• Enzyme Technology

Context:

• The growing demand for skilled professionals in biotechnology manufacturing necessitates advanced experimental training.
• Traditional biotechnology courses often lack practical exposure to industrial process management and complex problem-solving.
• Effective training requires bridging the gap between academic principles and real-world biomanufacturing operations.

Purpose:

• To develop a comprehensive biotechnology experiment course that equips students with practical skills for solving complex engineering problems in biomanufacturing.
• To integrate principles of enterprise site management and production processes into experimental biotechnology education.
• To enhance student competency in enzymatic production processes, specifically l-aspartate and l-alanine synthesis.

Summary:

• The course features a "Comprehensive Biotechnology Experiment" utilizing two-step enzymatic production of l-aspartate and l-alanine.
• It adopts an industrial operational model of four shifts and three operations, mirroring enterprise site management.
• Evaluation includes handover records and teamwork, assessing practical application and collaborative skills.

Impact:

• The developed experimental teaching process and assessment mechanism have demonstrated a positive teaching effect.
• This course serves as a valuable reference for advancing biotechnology experimental education.
• It aims to improve the training of future biotechnology engineers capable of managing complex production processes.