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Investigation of the intronic variant RHD:c.1154-31C>T designated as RHD*01EL.37

Xue Rui1, Hongjun Gao2, Yu Zhang1

  • 1Red Cell Reference Laboratory, Nanjing Red Cross Blood Center, Nanjing, China.

Vox Sanguinis
|February 27, 2023
PubMed
Abstract

No abstract available in PubMed .

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The key clinical manifestations of Rheumatic heart disease (RHD) include several distinct cardiac symptoms.Carditis, a hallmark of acute rheumatic fever, involves inflammation of the heart's endocardium, myocardium, and pericardium. Chronic RHD often results from recurrent episodes of carditis. Its symptoms include the following:Murmurs are caused by valvular damage, especially to the mitral and aortic valves. Mitral stenosis or regurgitation is common, with characteristic heart murmurs...
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