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Updated: Jun 15, 2026

Amide Coupling Reaction for the Synthesis of Bispyridine-based Ligands and Their Complexation to Platinum as Dinuclear Anticancer Agents
Published on: May 28, 2014
Bisnitramide-Bridged N-Substituted Tetrazoles with Balanced Sensitivity and High Performance
Ajay Kumar Chinnam1, Richard J Staples2, Jean'ne M Shreeve1
1Department of Chemistry, University of Idaho, Moscow, Idaho 83844-2343 United States.
Abstract:
In this study, a simple synthetic strategy for bridged bis(nitramide)-based N-substituted tetrazoles is described. All new compounds were isolated and fully characterized by sophisticated analytical techniques. The structures of the intermediate derivative and two final compounds were determined by single-crystal X-ray data. The structures of the intermediate derivative and two final compounds were determined by single crystal X-ray data. Thermostabilities and energetic properties of new bridged bisnitramide-based N-substituted tetrazoles were discussed and compared with known materials.
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