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Related Experiment Video

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Whole Mount Immunofluorescent Staining of the Neonatal Mouse Retina to Investigate Angiogenesis In vivo

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Published on: July 9, 2013

Avascular Peripheral Retina in Infants.

Şengül Özdek¹, Ece Özdemir Zeydanlı², Caroline Baumal³

¹Gazi University Faculty of Medicine, Department of Ophthalmology, Ankara, Türkiye.

Turkish Journal of Ophthalmology

|February 27, 2023

Summary

Diagnosing avascular peripheral retina in infants is challenging. This review covers key features of various pediatric retinal vascular disorders to aid clinicians.

Keywords:

Avascular retina Coats disease Norrie disease familial exudative vitreoretinopathy incontinentia pigmenti persistent fetal vasculature retinopathy of prematurity

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Quantification of Vascular Parameters in Whole Mount Retinas of Mice with Non-Proliferative and Proliferative Retinopathies

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Published on: March 12, 2022

Area of Science:

Ophthalmology
Pediatric Medicine
Vascular Biology

Background:

Avascular peripheral retina in infants is a common sign of pediatric retinal vascular disorders.
These conditions often pose significant diagnostic challenges for clinicians.
Early and accurate diagnosis is crucial for effective management and visual outcome.

Approach:

This review synthesizes information on differential diagnoses for infantile avascular peripheral retina.
It covers a range of conditions including retinopathy of prematurity, Coats disease, and rare genetic disorders.
Expert ophthalmologists provide insights into the key features of each disease.

Key Points:

Retinopathy of prematurity (ROP) and familial exudative vitreoretinopathy (FEVR) are common considerations.
Coats disease, incontinentia pigmenti, and Norrie disease present distinct vascular abnormalities.
Rare hematologic conditions and telomere disorders can also manifest with peripheral retinal avascularity.

Conclusions:

A comprehensive understanding of diverse pediatric retinal vascular disorders is essential.
This review aims to equip clinicians with the knowledge to differentiate between these challenging conditions.
Accurate diagnosis facilitates timely intervention and improves patient prognosis.