[Pruritus in pregnancy: consider the intrahepatic cholestasis of pregnancy]

In the case of generalized pruritus in pregnancy, dermatological diseases are often considered primarily and the patient is treated topically. In any case, intrahepatic cholestasis of pregnancy (ICP) should be clarified as a potentially child- and pregnancy-threatening disease. The leading symptoms are pruritus, especially on the palms and feet, and laboratory elevated bile acids (GS) and transaminases. Feared perinatal complications include prematurity, green/meconium-containing amniotic fluid, respiratory distress syndrome, or even intrauterine fetal death.