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Updated: Aug 8, 2025
Author Spotlight: Tracking Electrochemistry on Single Nanoparticles with Surface-Enhanced Raman Scattering Spectroscopy and Microscopy
Published on: May 12, 2023
Protocol for designing AuNP-capped Ag dendrites as surface-enhanced Raman scattering sensors for trace molecular
V S Vendamani1, Reshma Beeram1, S V S Nageswara Rao2
1Advanced Centre for Research in High Energy Materials (ACRHEM), DRDO Industry Academia - Centre of Excellence (DIA-COE), University of Hyderabad, Hyderabad, Telangana 500046, India.
Abstract:
Surface-enhanced Raman spectroscopy (SERS) is a label-free, non-destructive technique for rapid identification of molecules with the interest of public safety and forensics. In the current work, we present a detailed protocol for designing a SERS-active substrate comprising Au-nanoparticles-decorated Ag nano-dendrites for the trace detection of explosives, biomolecules, dye, and pesticides. We elaborate the procedure for studying near-field enhancements in plasmonic structures. This protocol also addresses some of the challenges faced in SERS experiments and the potential solutions to overcome them. For complete details on the use and execution of this protocol, please refer to Vendamani et al. (2022).1.
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