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Application of Granger Causality Analysis of the Directed Functional Connection in Alzheimer's Disease and Mild Cognitive Impairment
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Granger causality using Jacobian in neural networks.

Suryadi1, Lock Yue Chew1, Yew-Soon Ong2

  • 1School of Physical and Mathematical Sciences, Nanyang Technological University, Singapore 637371.

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Summary
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We introduce Jacobian Granger causality (JGC), a novel neural network method for time series analysis. JGC effectively identifies Granger causal variables, time lags, and interaction signs, outperforming existing methods.

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Area of Science:

  • Neuroscience
  • Dynamical Systems Analysis
  • Time Series Analysis

Background:

  • Granger causality is essential for understanding information flow in time series data.
  • Existing methods face challenges with nonseparability in dynamical systems.
  • Identifying causal relationships and variable importance in complex systems remains a challenge.

Purpose of the Study:

  • Introduce Jacobian Granger causality (JGC), a neural network-based approach.
  • Develop a variable selection procedure for inferring Granger causal variables.
  • Address limitations of traditional Granger causality methods, including nonseparability.

Main Methods:

  • Utilize the Jacobian matrix as a measure of variable importance within a neural network framework.
  • Implement a variable selection procedure based on significance and consistency criteria.
  • Compare JGC performance against established Granger causality approaches.

Main Results:

  • JGC demonstrates consistent performance in identifying Granger causal variables.
  • The method accurately determines associated time lags and interaction signs.
  • JGC effectively handles nonseparability issues common in dynamical systems.

Conclusions:

  • Jacobian Granger causality offers a robust and effective method for time series analysis.
  • The proposed variable selection procedure enhances the reliability of causal inference.
  • Neural network-based approaches like JGC advance the study of complex dynamical systems.