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Updated: Aug 8, 2025
04:57
Establishing a Competing Risk Regression Nomogram Model for Survival Data
Published on: October 23, 2020
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A comparative study of four thoracic mortality scores
Georg Schlachtenberger1, Fabian Doerr2, Hruy Menghesha2
1Department of Cardiothoracic Surgery, Heart Center, 14309University of Cologne, Cologne, Germany.
Asian Cardiovascular & Thoracic Annals
|March 2, 2023
Summary
Eurolung 2 and simplified Eurolung 2 models are best for predicting 30-day mortality in non-small cell lung cancer (NSCLC) patients undergoing surgery. These models offer superior risk stratification compared to Thoracoscore and Epithor.
Area of Science:
- Thoracic Surgery
- Surgical Oncology
- Pulmonary Medicine
Background:
- Increasing diagnosis of resectable non-small cell lung cancer (NSCLC) necessitates accurate risk prediction.
- Established scoring models require validation for predicting postoperative mortality.
Purpose of the Study:
- To validate and compare four risk scoring models: Thoracoscore, Epithor, Eurolung 2, and simplified Eurolung 2 (2b).
- To assess their efficacy in predicting 30-day mortality following anatomical pulmonary resection for NSCLC.
Main Methods:
- Retrospective analysis of 624 NSCLC patients undergoing anatomical pulmonary resection (2012-2018).
- Performance evaluation using Hosmer-Lemeshow goodness-of-fit (calibration) and ROC curves (discrimination).
- Comparison of Area Under the Curve (AUC) using DeLong's method.
Main Results:
- 30-day mortality rate was 2.2% (14 patients).
- Eurolung 2 and simplified Eurolung 2 demonstrated superior discrimination (AUC 0.82) compared to Epithor (0.71) and Thoracoscore (0.65).
- DeLong analysis confirmed significant superiority of Eurolung 2/2b over Thoracoscore (p=0.04).
Conclusions:
- Eurolung 2 and simplified Eurolung 2 are favorable scoring systems for predicting 30-day mortality in NSCLC surgery.
- Recommend Eurolung 2 or simplified Eurolung 2 for preoperative risk stratification in NSCLC patients.
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