Related Experiment Video
Updated: Aug 8, 2025

Comparing Bibliometric Analysis Using PubMed, Scopus, and Web of Science Databases
Published on: October 24, 2019
Measuring disadvantage: A systematic comparison of United States small-area disadvantage indices
Sophia Lou1, Salvatore Giorgi2, Tingting Liu3
1Technology and Translational Research Unit, National Institute on Drug Abuse, 251 Bayview Blvd., Baltimore, MD, 21224, USA.
Abstract:
Extensive evidence demonstrates the effects of area-based disadvantage on a variety of life outcomes, such as increased mortality and low economic mobility. Despite these well-established patterns, disadvantage, often measured using composite indices, is inconsistently operationalized across studies. To address this issue, we systematically compared 5 U.S. disadvantage indices at the county-level on their relationships to 24 diverse life outcomes related to mortality, physical health, mental health, subjective well-being, and social capital from heterogeneous data sources. We further examined which domains of disadvantage are most important when creating these indices. Of the five indices examined, the Area Deprivation Index (ADI) and Child Opportunity Index 2.0 (COI) were most related to a diverse set of life outcomes, particularly physical health. Within each index, variables from the domains of education and employment were most important in relationships with life outcomes. Disadvantage indices are being used in real-world policy and resource allocation decisions; an index's generalizability across diverse life outcomes, and the domains of disadvantage which constitute the index, should be considered when guiding such decisions.
Related Concept Videos
Wilcoxon Signed-Ranks Test for Median of Single Population
One-Way ANOVA: Equal Sample Sizes
Different sample means can result in different values for the variance estimate: variance between samples. This is because the variance between samples is calculated as the product of the sample size and the variance between the...
One-Way ANOVA: Unequal Sample Sizes
Area Computation by the Alternative Coordinate Method
Friedman Two-way Analysis of Variance by Ranks
Wilcoxon Rank-Sum Test

