AMD recapitulated in a 3D biomimetic: A breakthrough in retina tissue engineering
Sonal Dalvi1, Amit Chatterjee1, Ruchira Singh2
1Department of Ophthalmology, University of Rochester, Rochester, NY 14620, USA; Center for Visual Science, University of Rochester, Rochester, NY 14620, USA.
Cell Stem Cell
|March 3, 2023
Abstract:
Song et al. (Nature Methods, 2022) engineered a 3D model of the human outer blood-retina barrier (oBRB) that recapitulates key features of healthy and age-related macular degeneration (AMD)-affected eyes.1 We shine a spotlight on this tissue-engineering triumph that has the potential to transform preclinical studies of AMD and other eye diseases.
