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Published on: September 20, 2018
[Hereditary bradykinin angioedema. Case report]
Luiz Marcelo Pimenta E Silva1, Fernando Oliveira Dos Santos2, Flávia Rodrigues de Oliveira3
1Universidad Federal de San Pablo (UNIFESP). Departamento de Alergia e Inmunología Clínica. San Pablo SP, Brasil.
Introduction:
Hereditary angioedema is an autosomal dominant genetic disease, associated with increased levels of bradykinin. It is classified into 3 types according to the C1-INH enzyme. The diagnosis is clinical and laboratory. Its treatment is divided into short- and long-term and crisis prophylaxis.
Case Report:
40-year-old female patient who came to the emergency service for labial edema without resolution with corticosteroids. The tests for IgE, C4 and C1 esterase inhibitors had a low result. She currently uses danazol prophylactically and fresh frozen plasma in crises.
Conclusions:
Since it is a disease that considerably affects the quality of life, hereditary angioedema must be diagnosed and an effective treatment plan made to prevent or reduce its complications.
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