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Updated: Aug 10, 2026

Patient Derived Cell Culture and Isolation of CD133+ Putative Cancer Stem Cells from Melanoma
Published on: March 13, 2013
Abstract:
The cytologic characteristics of malignant melanoma of the rectum are discussed in the paper. The study was based on the data of examination of 13 cases (pigment-free tumor--6 cases). The basic cytologic features of malignant melanoma were diverse cellularity, presence of binuclear cells, and granules or diffuse inclusion of melanin. Three histologic patterns of tumor were identified: epithelioid, spindle-cell and polymorphous cell. Two cases of pigment-free malignant melanoma of the anorectal area were misdiagnosed as squamous cell carcinoma which was due to reactive changes developing in the cells of the stratified squamous epithelium.
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