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Updated: Aug 9, 2026

Isolation and Characterization of Tumor-initiating Cells from Sarcoma Patient-derived Xenografts
Published on: June 13, 2019
[Cytological diagnosis and cytological classification of lymphosarcomas]
Abstract:
The cell composition of tumour was studied in punch biopsies from 123 patients with lymphosarcoma; staining by Leishman method was used. General and particular cytologic criteria of tumour were determined. Cytologic verification of lymphosarcoma types and variants was performed according to WHO classification (1976) and was compared to the histological diagnoses. The following cell types and variants of tumour were distinguished as a result of identification of cytograms and standardization of cytologic diagnoses based on particular properties of cells: 1) lymphoplasmocytic lymphosarcoma: a) polymorphocellular, b) plasmacytoid; 2) prolymphocytic lymphosarcoma: a) from cells with roundish nuclei, b) from cells with split nuclei; 3) lymphoblastic lymphosarcoma: a) microlymphoblastic, b) macrolymphoblastic, c) from cells with tortuous nuclei; 4) immunoblastic lymphosarcoma; 5) lymphosarcoma not otherwise classifiable cytologically.
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