Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Filament Extrusion-Based Conductive TPU Composite Scaffolds Enable Superior Neuronal Growth and Synaptic Maturation In Vitro.

Engineering in life sciences·2026

Same author

Biomimetic electrospun scaffolds for engineered heart tissue: from design parameters to drug testing platforms.

Frontiers in bioengineering and biotechnology·2026

Same author

Impact of Ethylene Oxide Sterilization on PEDOT:PSS Electrophysiology Electrodes.

Sensors (Basel, Switzerland)·2026

Same author

Marine- and Plant-Based Nanoemulsion Platforms Enhance the Anticancer Activity of Curcumin In Vitro.

International journal of molecular sciences·2026

Same author

Nanocomposite GelMA Bioinks: Toward Next-Generation Multifunctional 3D-Bioprinted Platforms.

Small (Weinheim an der Bergstrasse, Germany)·2025

Same author

Digital light processing 3D bioprinting of biomimetic corneal stroma equivalent using gelatin methacryloyl and oxidized carboxymethylcellulose interpenetrating network hydrogel.

Biofabrication·2025

Same journal

Four-in-one multifunctional CoCu-NC@AuPt nanozyme integrated M13 phage-displayed nanobody based multimodal lateral flow immunoassay for bovine lactoferrin detection.

Biosensors & bioelectronics·2026

Same journal

A novel capillary-driven dual-mode imaging flow cytometry system for malaria parasite detection and quantification.

Biosensors & bioelectronics·2026

Same journal

Liver-targeted alkaline phosphatase-activatable fluorescent probe for imaging liver fibrosis and screening anti-fibrotic natural products.

Biosensors & bioelectronics·2026

Same journal

GLASS-seq: a gel-anchored, ligation-assisted, scalable biosensing platform for low-cost regional spatial transcriptomics.

Biosensors & bioelectronics·2026

Same journal

CRISPR/Cas12a-based dual-modal signal platform using MIL-101(Fe) for colorimetric and electron spin resonance detection of HPV-16 nucleic acid.

Biosensors & bioelectronics·2026

Same journal

Fully automated centrifugal microfluidic system for self-calibrating isothermal nucleic acid quantification.

Biosensors & bioelectronics·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Aug 8, 2025

Chronic Implantation of Multiple Flexible Polymer Electrode Arrays

Chronic Implantation of Multiple Flexible Polymer Electrode Arrays

Published on: October 4, 2019

Hollow ring-like flexible electrode architecture enabling subcellular multi-directional neural interfacing.

Venkata Suresh Vajrala¹, Kamil Elkhoury¹, Sophie Pautot²

¹Laboratory for Analysis and Architecture of Systems (LAAS), CNRS, Toulouse, France.

Biosensors & Bioelectronics

|March 4, 2023

Summary

This summary is machine-generated.

Researchers developed novel hollow ring neural electrodes for improved brain-computer interfaces. These electrodes offer better signal resolution and cell integration compared to traditional designs, advancing neural recording and stimulation.

Keywords:

3D neural networks Electrophysiology Hollow ring electrode Microelectrode array Neural interface PEDOT:PSS

More Related Videos

Fabrication of High Contact-Density, Flat-Interface Nerve Electrodes for Recording and Stimulation Applications

Fabrication of High Contact-Density, Flat-Interface Nerve Electrodes for Recording and Stimulation Applications

Published on: October 4, 2016

Syringe-injectable Mesh Electronics for Stable Chronic Rodent Electrophysiology

Syringe-injectable Mesh Electronics for Stable Chronic Rodent Electrophysiology

Published on: July 21, 2018

Related Experiment Videos

Last Updated: Aug 8, 2025

Chronic Implantation of Multiple Flexible Polymer Electrode Arrays

Chronic Implantation of Multiple Flexible Polymer Electrode Arrays

Published on: October 4, 2019

Fabrication of High Contact-Density, Flat-Interface Nerve Electrodes for Recording and Stimulation Applications

Fabrication of High Contact-Density, Flat-Interface Nerve Electrodes for Recording and Stimulation Applications

Published on: October 4, 2016

Syringe-injectable Mesh Electronics for Stable Chronic Rodent Electrophysiology

Syringe-injectable Mesh Electronics for Stable Chronic Rodent Electrophysiology

Published on: July 21, 2018

Area of Science:

Neuroscience
Biomedical Engineering
Materials Science

Background:

Implantable neural microelectrodes are crucial for neuroscience research and neuroprosthetics.
There is a need for advanced electrodes offering selectivity, stealth, and robust neural integration.
Current electrodes face challenges in maintaining long-term viability and signal quality.

Purpose of the Study:

To introduce a novel Hollow Ring-like electrode for sensing and stimulating neural activity.
To evaluate the electrode's performance in three-dimensional neural networks.
To compare the hollow ring electrode with traditional disk-type electrodes.

Main Methods:

Fabrication of Hollow Ring-like electrodes.
Coating electrodes with poly(3,4-ethylenedioxythiophene) polystyrene sulfonate (PEDOT:PSS).
Characterization of electrical properties (impedance, charge injection).
In vitro testing on 3D neuronal networks for signal recording and burst detection.

Main Results:

Hollow Ring electrodes exhibit significantly lower impedance (7 MΩ μm²) and higher charge injection capacity (15 mC/cm²).
The ring design promotes cell growth and enhances the electrical-neural interface.
Improved signal-to-noise ratio (SNR) and burst detection were observed compared to disk electrodes.
Enhanced neural signal resolution from 3D networks.

Conclusions:

The Hollow Ring electrode design shows great potential for next-generation neural interfaces.
This novel architecture facilitates improved neural recording and stimulation.
The findings support applications in physiological studies and neuromodulation.