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Related Concept Videos

Cardiomyopathy II: Dilated Cardiomyopathy01:30

Cardiomyopathy II: Dilated Cardiomyopathy

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Dilated cardiomyopathy, or DCM, is a progressive myocardial disorder characterized by ventricular chamber dilation and contractile dysfunction.EtiologyVarious factors can cause DCM, including hypertension and heavy alcohol intake, which contribute to the weakening and enlargement of the heart muscle. Viral infections, such as Coxsackievirus B, adenoviruses, and influenza, can lead to DCM by causing inflammation and damage to heart tissue. Certain chemotherapeutic agents, including daunorubicin,...
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Cardiomyopathy I: Introduction and Classification01:25

Cardiomyopathy I: Introduction and Classification

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Cardiomyopathy, or CMP, is a group of diseases affecting the myocardial structure, impairing its ability to pump blood effectively. This condition can lead to arrhythmias, heart failure, or sudden cardiac death.Cardiomyopathies are classified into primary and secondary categories:Primary Cardiomyopathy refers to conditions involving only the heart muscle that are often idiopathic (of unknown cause) or genetic. They primarily affect the myocardium without the involvement of other systemic...
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Cardiomyopathy III: Hypertrophic Cardiomyopathy01:29

Cardiomyopathy III: Hypertrophic Cardiomyopathy

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Hypertrophic cardiomyopathy, or HCM, is an autosomal dominant genetic disorder characterized by asymmetric left ventricular hypertrophy without ventricular dilation. It is more common in men and is typically diagnosed in young, athletic adults.EtiologyHCM is primarily genetic and is caused by mutations in genes encoding sarcomeric proteins. Researchers have identified over 1400 mutations across at least 11 different genes. Among these, the most frequently occurring mutations are found in the...
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Cardiomyopathy IV: Restrictive Cardiomyopathy01:29

Cardiomyopathy IV: Restrictive Cardiomyopathy

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Restrictive cardiomyopathy (RCM) is a rare heart muscle disease characterized by impaired ventricular filling due to stiffened ventricular walls, leading to significant diastolic dysfunction.EtiologyRestrictive cardiomyopathy can arise from both inherited and acquired diseases, many of which are systemic. It is categorized into four main types: infiltrative, storage, non-infiltrative, and endomyocardial diseases.Infiltrative diseases, such as amyloidosis, lead to RCM by depositing amyloid...
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Myocarditis I: Introduction01:21

Myocarditis I: Introduction

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Myocarditis is inflammation of the myocardium, which is the muscular layer of the heart.EtiologyMyocarditis has a diverse etiology, including a wide range of infectious and non-infectious causes:Infectious CausesViral: Common viruses include Coxsackie A and B, adenovirus, parvovirus B19, enteroviruses, and influenza A.Bacterial: Examples include infections caused by Streptococcus, Staphylococcus, and Mycoplasma species.Rickettsial: Infections like Rocky Mountain spotted fever can result in...
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Cardiomyopathy V: Interprofessional Care01:29

Cardiomyopathy V: Interprofessional Care

21
Managing cardiomyopathy involves addressing underlying or precipitating causes, treating heart failure with medications, and implementing dietary changes and a balanced exercise and rest regimen.Lifestyle ModificationsCardiomyopathy patients should adopt a low-sodium diet to reduce fluid retention and manage heart failure. A personalized exercise and rest plan helps maintain physical fitness without overstraining the heart. Avoiding alcohol and tobacco is essential to prevent further damage to...
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A Doxorubicin-Induced Murine Model of Dilated Cardiomyopathy In Vivo
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SARS-CoV-2 dilated cardiomyopathy.

Manuel Felipe Cáceres-Acosta1, Bairon Díaz Idrobo2, Diana Carolina Urbano Albán2

  • 1Cardiologist, Cardiovascular Line of the Health Research Group (GIS) and Postgraduate Professor, University of Cauca Hospital Universitario San José, Carrera 6 #10N-142, 190002 Popayán, Cauca, Colombia.

The British Journal of Cardiology
|March 6, 2023
PubMed
Summary
This summary is machine-generated.

Severe COVID-19 infection caused viral myocarditis and dilated cardiomyopathy in a young, obese male. Despite treatment, the patient experienced heart failure and unfortunately died.

Keywords:
COVID-19SARS-CoV-2cardiac magnetic resonancedilated cardiomyopathymyocarditis

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Area of Science:

  • Cardiology
  • Infectious Diseases
  • Virology

Background:

  • Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is an emerging cause of viral myocarditis.
  • Viral myocarditis can lead to serious complications, including dilated cardiomyopathy.

Purpose of the Study:

  • To describe a case of severe myocardial involvement in a young, obese male patient due to SARS-CoV-2 infection.
  • To highlight the clinical presentation, diagnostic findings, and outcome of SARS-CoV-2-induced viral myocarditis.

Main Methods:

  • Case report of a young, obese male patient with confirmed SARS-CoV-2 infection.
  • Clinical assessment including chest pain, cardiac enzymes, and electrocardiography.
  • Cardiac imaging with echocardiogram and magnetic resonance imaging (MRI).

Main Results:

  • The patient presented with symptoms and biochemical markers indicative of myocardial injury.
  • Echocardiogram showed dilated heart disease with reduced ejection fraction.
  • Cardiac MRI confirmed findings consistent with viral myocarditis.
  • The patient did not respond to systemic steroids or standard heart failure management.

Conclusions:

  • SARS-CoV-2 can cause severe viral myocarditis with dilated cardiomyopathy.
  • This case highlights a severe outcome in a young, obese patient.
  • Refractory disease course and mortality underscore the potential severity of SARS-CoV-2 cardiac involvement.