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Updated: Aug 7, 2025

Production and Visualization of Bacterial Spheroplasts and Protoplasts to Characterize Antimicrobial Peptide Localization
Published on: August 11, 2018
Review of the Specific Features, and New Demands for Antibacterial Peptides
Hisham N Farrag1, Hirokazu Shimooka1, Mitsuru Kitamura1
1Department of Applied Chemistry, Kyushu Institute of Technology, Tobata-ku, Kitakyushu 804-8550, Japan.
Abstract:
The emergent disaster of antimicrobial resistance developed by virulent bacteria has highlighted the need to investigate substitutes for the presently existing antibiotics. Antibacterial peptides (ABPs) have arisen as promising substitutes because of their unique killing effect on bacteria: bacterial resistance toward ABPs is negligible. ABPs have many beneficial subsidiary effects, such as protection of labile bioactive compounds, and they can be covalently connected to different materials to enhance their antibacterial effect. Many researchers have investigated many applications of these peptides recently, such as in a variety of pharmaceutical dosage forms and wastewater treatment.
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